Nano Micromotors (NMS) are tiny structures capable of converting various forms of energy into mechanical motion at the microscopic and nanoscale scales. Operating in low inertia and low Reynolds number environments, NMS has a wide range of potential applications, especially in the biomedical and environmental sciences fields. Surface-enhanced Raman scattering (SERS) is a powerful analytical technique that enhances the Raman signal intensity of molecules, enabling highly sensitive detection and analysis of trace substances. The combination of NMS and SERS technology enables high-precision and localized hypersensitivity and real-time imaging in areas such as chemistry and cell biology, medical diagnostics and prognosis. In the past, NMS and SERS technologies have been widely used in different fields, but the potential of their combination in real-time imaging and high-sensitivity perception is only beginning to be explored.
Based on the above questions,RoviraWilgilli Universityramona.alvarez-pueblaTeam of professorsA nano-micromotor-driven SERS was constructed for high-sensitivity and spatial control sensing. The study, titled "Nano Micromotor-drivensers for Highly Sensitive and Spatially ControlledSensing", was published in Advanced Functional Materials.
Figure 1 shows, (a) Chemically driven NMS. The decomposition of HO illustrates three possible mechanisms for generating motion: self-electrophoresis, bubble propulsion, or self-diffusion electrophoresis. b-a) Schematic diagram of the five main motions of magnetically driven NMS: linear operation, helix, oscillation, rotation and surface assist (rolling and tumbling). b-b) Electrokinetic effect of motorized tweezers on transport and positioning.
In summary, the synergy between SERS and nanomotors is expected to transcend existing boundaries. By transporting SERS substrates to a designated location, nanomotors facilitate in-situ and real-time analysis of complex chemical and biological samples. This integration will revolutionize healthcare, environmental science, and materials engineering, heralding a new era of detection, quantification, and bioimaging. The desire to increase sensitivity, specificity, and versatility drives innovation, addresses contemporary challenges, and uncovers new opportunities in analytical science.
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