Now it is very good for women with poor fertility to solve this problem through the test tube, in the process of test tube, the fresh embryo is divided into different embryo levels of the standard, which is divided into first, second, first and fourth. Primary and secondary embryos are of good quality, and the amount of primary embryo fragments is less than 10%, *embryos are usable, and fourth degree embryos are inferior and generally considered unsuitable for transfer.
Criteria for the classification of fresh embryos in vitro
With the continuous progress of our science and technology and medicine, the technology of IVF has gradually improved, and now IVF technology has been one of the important means of infertility, different grades of fresh embryos, the impact on IVF is not the same, so the level of IVF fresh embryos is divided, so that the quality and development potential of embryos can be better evaluated, so as to select better quality embryos for transfer, the following is a detailed introduction to the division criteria of IVF fresh embryo level.
1. The first level of embryos refers to high-quality embryos, generally this type of embryo has uniform size, regular appearance, normal blastomere refraction, no fragments or the amount of fragments is less than 10%, and the zona pellucida is complete and smooth, etc., which is an ideal embryo for IVF.
2. Secondary embryos belong to good embryos, these embryos are refractive globules, irregular appearance, and fragments are less than 20%, which is the most common embryo. There are certain irregularities in the size and morphology of embryonic somatic cell masses, as well as in the color and relative density of individual cells.
3. **Embryo is also known as general embryo, and there are serious irregularities in the size and shape of embryonic cell mass and the color and density of individual cells. The size of the cells will be obviously Xi uneven, and there will be obvious granular phenomena, with a fragmentation rate of 21%-25%. If this is the case, the doctor will inform both parties that this type of guinea fetus is generally not used for fertility at this time.
4. Fourth-level embryosThe fourth-level fresh embryo belongs to the embryo that cannot be used, the cell size is seriously uneven, the cytoplasm has serious granules, and the fragmentation is 50%. To sum up, we also have a clear understanding of the classification criteria for the IVF embryo level, which is one of the important indicators for judging the quality of embryos and the success rate of transfer.
Before making a test tube, we can learn more about the test tube, and the more we know, we can better ensure our mastery of the test tube process, and we will not be like a headless fly.
Basis for the criteria for the classification of first-class embryos
We all know that in IVF**, the level of the embryo is directly related to the final success rate of IVF, and the first-level embryo is the high-quality embryo in the IVF technology, and we all hope that we use the first-level embryo for transfer, so the basis for the division of the first-level embryo is unclear to many people, and we will introduce the specific content of these indicators in detail below to help you understand the first-level embryo more comprehensively.
1. The number of blastomeresFirst-level embryos usually have 6-8 cells, which is a manifestation of embryonic development to a certain stage. If the number of blastomeretes is less or more than this range, it may indicate a problem with embryonic development, which will affect subsequent development and the success rate of transfer.
2. The size of the schizosphere should be uniform, and the size and shape of each cell should be similar. When assessing split-glob size, doctors usually consider factors such as the diameter and volume of each cell.
3. UniformityWhether the quality and morphology of each cell in the embryo are similar, there is no obvious abnormality, and the uniformity is relatively high.
4. Morphological regularThe morphology should be regular, round or oval, with clear edges, no obvious depressions or protrusions, if the embryo morphology is irregular, it may be due to some factors that lead to abnormal embryonic development, such as chromosomal abnormalities, gene mutations, etc., then it will affect the division of embryo grade.
5. The fragments of the first-class embryo should be as little as possible, usually the amount of fragmentation is less than 10%, compared with the normal form of the embryo, the embryo with fragmentation, the heritability and incidence of cell abnormalities are obviously high, and the transfer of severe fragmented embryos may also lead to fetal malformations. The more fragments of the embryo, the worse its growth potential may be. At present, the number of embryo fragments has become an important indicator of the quality of the embryo.
To sum up, the division of first-class embryos is based on many aspects, from which we can also see that first-level embryos are more difficult to cultivate, after all, its requirements in all aspects are relatively high, of course, we do not have to choose first-class embryos in the process of IVF, like other grades can also be transferred, doctors will choose the right file for us according to our actual situation.