The adhesion determination methods of plasters, patches, plasters and transdermal patches should refer to the Chinese Pharmacopoeia, which includes four test indicators: initial adhesion, adhesion, peel strength and adhesion, which are used to evaluate the adhesion of plasters and patches. This article only focuses on the testing items, principles and instruments related to the initial adhesion tester (known as the initial force tester in the industry).
Shandong Quankeruida Instrument and Equipment***qktesterAs a manufacturer of testing instruments for pharmaceutical packaging materials, pharmaceutical patches and plasters, in order to facilitate customers to quickly grasp or carry out the methods and instruments required for adhesion determination, this material is specially compiled for reference.
1. The importance of adhesion testing
The adhesion determination method refers to the Chinese Pharmacopoeia, which includes four indicators: initial adhesion, adhesion, peel strength and adhesion, which are used to evaluate the adhesion of plasters and patches. where adhesion.
It is an important indicator for detecting the adhesion of the adhesive surface of the plaster and the adhesive surface of the patch and the adhesion of the adhesive to the adhesive.
2. Adhesion test method
According to the table on page 143 of Part IV of the Pharmacopoeia (2020 Edition), in general, it is recommended that the adhesion of rubber plaster should be 3-6N (3000-6000mn), and the adhesion of gel plaster should be 1000-2000mn(Note that this value should be the test data of two strips with a width of 12mm, that is, the total width is 24mm).
3. Instruments used in adhesion testing (adhesion tester, adhesion testing machine).
Adhesion tester (Quankeruida, NZL-01) adhesion tester.
This adhesion tester (adhesion tester) is strictly in accordance with the provisions of the pharmacopoeia.
It has the functions of hierarchical authority management, password secret, audit trail and so on.
The manuscript comes from the source: Shandong Quankeruida Instruments and Equipment***Searchable Quankeruida).