What causes mental disorders?At present, the research on the science and mechanism of mental disorders has begun to comprehensively explore and analyze the science of mental disorders from biological, psychological, social and other aspects. In addition, the prospect of mental disorders** research is also challenging. Let's take a look.
First, the main **:1. Biological factors:(1) Genetic factors: The family, twins and foster children of patients with mental disorders are studied by the research methods of population genetics (i.e., genetic epidemiology) to confirm that mental disorders have a high genetic predisposition, the heritability of autism is as high as 90%, the heritability of mental ** disorder and bipolar disorder is also as high as 80%, the heritability of alcohol abuse dependence is 60%, and the heritability of major depression and panic disorder is relatively low at 40% (heritability refers to the part of a population that can be explained by genetic effects);The study also found that the inheritance pattern of mental disorders does not conform to the laws of Mendelian inheritance, and is a complex multifactorial genetic disorder.
2) Neurobiochemical factors: Through the effectiveness of existing drugs on mental disorders, it has been found that monoamine neurotransmitters and amino acid neurotransmitters may be involved in the pathogenesis of mental disorders, and in-depth research on neuropeptides and neurotrophic factors suggests that these two types of substances are also very likely to be involved in the pathophysiological process of mental disorders. (3) Endocrine factors: The endocrine system is regulated by the hypothalamus of the nervous system, and in turn, the nervous system is also regulated by the endocrine system, and the two are very closely related. The high comorbidity rate of endocrine dysfunction and psychiatric disorders, especially affective disorders, suggests that neuroendocrine disorders may be related to the occurrence and development of psychiatric disorders. (4) Neurodevelopmental abnormalities: The theory of mental development holds that the brain of patients with neurodevelopmental disorders fails to develop normally from the beginning, and due to the interaction between heredity and certain mental development risk factors, some neuropathological changes occur during brain development in the embryonic period, and the immediate effect of these changes is not significant.
5) Infection: As early as the early 20th century, we have known that infectious factors can affect the central nervous system and produce mental disorders. For example, sexually transmitted Treponema pallidum first causes symptoms of the reproductive system, and after years of incubation, enters the brain, causing neurosyphilis. Neurosyphilis is characterized by degeneration of the nervous system, manifested by dementia, psychotic symptoms, and paralysis. 2. Psychological and social factors: Psychological and social factors can play an important role in the onset of mental disorders as causative factors, as well as related factors to affect the occurrence and development of mental disorders, and can also play an important role in the occurrence and development of physical diseases. Clinically, the main mental disorders related to acute stress are acute stress response and post-traumatic stress disorder. In addition, different personality traits are more likely to develop mental disorders. 2. Predisposing factors:1. Immigrants and ethnic minorities: Relevant studies have found that the incidence of mental illness is highest in inner urban areas with serious ethnic conflicts, large floating populations, and chaotic social organizations. The results showed that ethnic minority identity may be one of the pathological factors in the pathogenesis of mental disorders. The association between ethnic minority groups and mental disorders has been found in both first- and second-generation immigrants, as well as in non-immigrant minorities, suggesting that there may be differences in the mechanisms by which immigrant and minority status mediate the onset of mental disorders. 2. Urbanization environment: The results show that the longer the exposure time of children and adolescents in a highly urbanized environment, the higher the risk of developing mental disorders in adulthood, and there is a certain dose-response relationship between the two. This suggests that urbanization exposure may play an important role in mental disorders**. 3. Childhood trauma: Relevant studies have found that childhood treatment is associated with physical abuse and hallucinations, delusions and thinking disorders in adulthood. 4. Use: The use of ** and the use of mental disorders ** are not only related to psychosis, randomized pilot studies have shown that d-9-tetrahydro**phenol (the main psychogenic component in **) can cause transient psychiatric symptoms and cognitive impairment in healthy volunteers, and individuals with genetic risk show more significant psychotic reactions. 5. Others: Factors that cause mental disorders may also include trauma, alcohol consumption, pregnancy injuries, cancer and other factors.