In our daily lives, we may often hear the term Parkinson's disease. Parkinson's disease is a common neurodegenerative disease that presents with symptoms such as resting tremor, bradykinesia, muscle rigidity, and postural balance disorders. Currently, medopar (dopaserazine tablets) is one of the most commonly used drugs for Parkinson's disease. However, some patients experience "end-of-dose phenomena" after using Medopa, what is going on?
Dr. Xie Hua. "End-of-dose phenomenon" refers to the gradual weakening of the efficacy of drugs in the process of long-term use of drugs such as medopa ** Parkinson's disease, or even ineffective. Specifically, the patient's symptoms are relieved for a period of time after the drug, but over time, the effect of the drug gradually weakens, and the patient's symptoms appear again or even worsen. This has a serious impact on the quality of life of patients.
a.Long-term use of drugs: Long-term use of medopar can cause the body to develop resistance to drugs, leading to a decrease in the effectiveness of the drugs.
b.Disease progression: Parkinson's disease is a progressive disease, and as the disease progresses, the effect of the drug gradually decreases.
c.Improper dosing: If the drug is used incorrectly, it can also lead to the occurrence of end-of-dose phenomena.
Dr. Xie Hua. Xie Hua, a traditional Chinese medicine physician from Beijing Tongshitang, said: The following 6 methods can reduce the degree of the phenomenon of the end of the dose!1. Adjust the dosage: Under the guidance of the doctor, adjust the dosage of medopar appropriately to achieve the best effect.
2. Combination of drugs: Under the guidance of doctors, Medopa can be combined with other drugs for Parkinson's disease to enhance the efficacy.
3. Traditional Chinese medicine conditioning: For Parkinson's disease patients who are ineffective in some drugs, traditional Chinese medicine conditioning is the best choice.
4. Exercise: Exercise is an important adjunct that can help patients improve symptoms of muscle strength, balance and coordination. At the same time, appropriate exercise can also improve the psychological quality and quality of life of patients.
5. Psychological support: Patients with Parkinson's disease are often accompanied by psychological problems such as depression and anxiety, so it is very important to give appropriate psychological support. Family members and society should pay attention to the mental health status of patients and provide care and support.
5. Reasonable lifestyle: A reasonable lifestyle (such as healthy diet, good sleep Xi, avoiding overwork, etc.) can help improve the physical condition and quality of life of patients.
6. Actively participate in training: Under the guidance of doctors, actively participate in training (such as physics, occupation, etc.) to help improve patients' symptoms and quality of life.
Dr. Xie Hua. The "end-of-dose phenomenon" is a common problem encountered by patients with Parkinson's disease during the use of drugs such as Medopa**. Understanding the causes and manifestations of this phenomenon and adopting appropriate coping strategies (such as adjusting the dosage of medications, combining drugs, traditional Chinese medicine conditioning, exercise**, psychological support, reasonable lifestyle and active participation in training**) can help improve the quality of life of patients. In the face of this problem, patients and their families should actively communicate with doctors to find the most suitable solution.