With the increasing number of hypertensive patients, there are more and more antihypertensive drugs to choose from in clinical practice, but whether it is amiloride, a diuretic antagonist for lowering blood pressure, or the more common calcium antagonist dipine, after continuous medication, similar manifestations will occur, that is, the effect will gradually deteriorate.
In this regard, many people believe that long-term drug use makes the body resistant, so it will lead to the deterioration of the effect of the same amount of drugs, and it is often necessary to increase the dosage to maintain the efficacy.
But in fact, antihypertensive drugs are different from antibacterial drugs or psychotropic drugs, and there is no so-called drug resistance, and if you take antihypertensive drugs on time and in accordance with the amount, but the antihypertensive effect is not obvious, perhaps due to the influence of these three factors, it is recommended that you pay attention.
1.Secondary hypertension
According to modern medicine, there are two main types of hypertension, namely primary hypertension and secondary hypertension. Essential hypertension is a symptom of hypertension caused by the aging and reduced flexibility of blood vessels, coupled with the blockage of blood vessel walls and the increase in blood viscosity, and accounts for a higher proportion of hypertension cases.
Secondary hypertension is mostly a complication of other diseases, such as diabetes, thyroid disorders, neck diseases, etc., which may be the trigger. Secondary hypertension usually requires treatment of the disease itself, and if you only take antihypertensive drugs but ignore the prevention and treatment of the root cause, then the effect is naturally poor.
Therefore, friends who can't lower their blood pressure should pay attention to whether they have other manifestations of metabolic syndrome, and the use of combined ** may be able to achieve better results.
2.Changes in physical condition
Some friends will find that their blood pressure can indeed be kept within a relatively safe range for a period of time when they first take medicine, but as time goes by, the effect of the drug gradually deteriorates, and the peak blood pressure is no longer "safe". This change is likely to be caused by a change in the patient's own physical condition.
As the patient ages, the patient's own vascular health will continue to be impaired, and the flexibility of its inner wall will also decline simultaneously, and when the "quantitative change" gradually accumulates into "qualitative change", the patient will find that the effect of the same dose of antihypertensive drugs no longer seems to be obvious.
At this time, the patient should contact the attending doctor as soon as possible to adjust the type and amount of medication appropriately, and at the same time, it is also necessary to adjust the Xi of his own life habits to avoid further deterioration of the vascular condition.
3.Limitations of drug use
As mentioned earlier, there is no inherently resistant antihypertensive drugs, but each drug does have limitations. In the actual process, patients often need to be conditioned by using a combination of **, so that blood pressure can be better controlled.
Therefore, when taking drugs for a long time, with the subtle changes in physical conditions, the effect of the same drug will gradually change.
All in all, hypertension is a long-term and slow process, patients should not pin all their hopes on drugs in the process of conditioning, develop a healthy and reasonable lifestyle and diet Xi habits, and then adjuvant medication to regulate blood pressure, so as to play a positive role in the improvement of prognosis and disease.
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