Human serum albumin thiol (HAS-SH) is a human serum albumin containing thiol functional groups. It has a wide range of applications in the biomedical field, mainly including the following:
1.Drug delivery: HAS-SH can be used as a carrier for drugs, and the targeted delivery of drugs can be achieved by covalently binding with drug molecules. For example, combining an anti-cancer drug with HAS-SH can enhance the accumulation of the drug in tumor tissue and reduce toxicity to healthy tissue.
2.Metal ion trapping: HAS-SH can be selectively associated withMetal ionsbinds to form stable complexes. This property can be used for ** metal poisoning, such as heavy metal poisoning and iron poisoning. For example, HAS-SH, which is bound to iron ions, can be used for iron overload such as thalassemia.
3.Antioxidants: HAS-SH has a strongerAntioxidant activity, which can help reduce oxidative stress damage within cells. This has potential applications for some diseases related to oxidative stress, such as cardiovascular diseases and neurodegenerative diseases.
4.Immunomodulation: HAS-SH can regulate the function of the immune system, promoting:Activity of immune cellsand enhancementsImmune response。This property can be used for immune-related diseases such as autoimmune diseases and infectious diseases.
In general, HAS-SH, as a human serum albumin with thiol functional groups, has potential application value in drug delivery, metal ion capture, antioxidant and immune regulation. It provides new ideas and methods for research and clinical practice in the field of biomedicine.