Clofazimine is an anti-leprosy and tuberculosis drug, but it may have some adverse effects during use. The adverse effects of clofazimine are described in detail below, so that patients and their families can understand and take countermeasures.
1. Systemic adverse reactions.
The most common systemic adverse reactions of clofazimine include hyperpigmentation, dryness, and itching. These symptoms usually appear within a few weeks of taking the drug and can last for months or even years. **Pigmentation is manifested as uniform pigmentation of the whole body, but there are also some patients who have **uneven pigmentation. Dryness manifests as dryness, scaling, and itching, often accompanied by chapped lips and mouth sores.
2. Adverse reactions of the digestive system.
Clofazimine also has a certain effect on the digestive system, and some patients will experience gastrointestinal reactions such as nausea, vomiting, and loss of appetite. These symptoms are generally mild, but a small number of patients may experience severe gastrointestinal reactions such as stomach ulcers and bleeding.
3. Systemic adverse reactions.
Clofazimine may also cause some systemic adverse reactions, such as fever, fatigue, muscle pain, headache, etc. These symptoms are generally mild, but a small number of patients will have severe systemic reactions, such as hepatitis and nephritis.
4. Adverse reactions of the blood system.
Clofazimine also has a certain effect on the blood system, and some patients will have anemia, leukopenia and other blood system reactions. These symptoms are generally mild, but a small number of patients may experience severe hematologic reactions, such as thrombocytopenia.
5. Allergic reactions.
Clofazimine may also cause allergic reactions such as rashes, hives, etc. These symptoms are generally mild, but a small number of patients may experience severe allergic reactions, such as anaphylactic shock.
6. Other adverse reactions.
In addition to the common adverse reactions mentioned above, clofazimine may also cause some other adverse reactions, such as insomnia, anxiety, etc. These symptoms are generally mild, but a small number of patients will have severe psychiatric symptoms, such as psychosis.
In general, clofazimine has more adverse effects, but most of the symptoms are mild and can be relieved by reducing the dose or stopping the drug. If the patient experiences serious adverse reactions, they should seek medical attention and consult their doctor for advice.