As a person who has been engaged in the cell industry for nearly 10 years, people often ask: does the country allow stem cells to intervene in diabetes?
First of all, please recognize one factThere is currently no drug on the market for stem cellsThis is the basis for people to recognize stem cells, and I have always believed that the real recognition is the recognition after understanding the real situation of this matter.
In fact, stem cells have been in the ""Gray area”。Why?
Because according to the national policy, the current stem cell diabetes has not been explicitly allowed, has been in the stage of "some people feel effective after using and privately use", the country has also been promoting the development of the cell industry, and also understands that the cell industry needs funds, therefore, as long as the cell institution does cells in a down-to-earth manner, does not engage in fraud, not because of stem cell problems, will not be investigated.
Therefore, if strictly speaking, stem cell diabetes is still in the gray area, and it has not entered the service list of tertiary hospitals, and can only be done in some cell institutions.
Next, let's take a look at the mechanism of action of stem cells in diabetes
1. Improve the function of pancreatic islet cells, which may be one of the mechanisms of action for its intervention in diabetes.
At present, it is believed that both type 1 and type 2 diabetes mellitus are actually caused by the dysfunction or damage of pancreatic islet cells in the body, resulting in insufficient insulin secretion and causing the onset and aggravation of diabetes.
Clinical studies have found that after stem cells enter the human body, they can promote the proliferation of cells in damaged islets through homing, chemotaxis and migration, or promote the proliferation of cells in damaged islets through cytokines, so as to repair and regenerate pancreatic islet cells, and can inhibit apoptosis, in short, protect and promote the repair and regeneration of pancreatic islet cells. At the same time, it can directly differentiate into insulin-secreting cells or promote the differentiation of ductal cells and pancreatic islet progenitor cells into insulin-secreting cells.
2. Anti-inflammatory and immune regulatory mechanisms
Studies have found that immune imbalance is also one of the key factors in the pathogenic mechanism of diabetes. Usually, the inflammatory environment can accelerate the destruction of pancreatic islet cells, resulting in insufficient insulin secretion in the body, which can induce or aggravate diabetes. Therefore, improving the body's microenvironment and regulating immunity through stem cells is also one of its important mechanisms.
3. Regulate the mechanism of angiogenesis
Vascular problems can be described as one of the important factors in the occurrence of diabetes complications, and it is worth noting that stem cells may promote tissue repair by regulating the production of blood vessels, preventing and improving diabetes complications.
Overall, the potential of stem cells to intervene in diabetes has been confirmed in many experiments. Stem cells can not only improve the function of pancreatic islet cells, regulate immune mechanisms, improve insulin resistance and insulin secretion, but also improve the diabetes microenvironment by regulating the formation of new blood vessels, so as to achieve the best diabetes and related complications.
Hundred Families Support Program Finally, to what extent can stem cell **diabetes go?
At present, stem cell intervention for diabetes can generally be achieved".Lowering blood sugar, reducing drug use, preventing and intervening in diabetes complicationsUnless a very small number of people have just suffered from diabetes, it is almost impossible for others to want to have diabetes, but it is not excluded that with the progress of cell technology, there will be new cell technology that can achieve diabetes, let's wait and see!