This article is from "Nankai Sun Pharmacist", which is used for medical science popularization for reference. The main active ingredients of Danshen are Danshensu and Tanshione, which have the functions of anti-peroxidative damage, protect myocardium, reduce myocardial oxygen consumption, improve myocardial energy metabolism, anti-platelet aggregation, and improve microvascular circulation, the main active ingredient of Panax notoginseng is Panax notoginseng saponins, which have anticoagulant, anti-inflammatory, protect vascular endothelial function, inhibit vascular intimal proliferation and lipid deposition, Anti-platelet aggregation and other effects, borneol is an adjuvant drug, which can promote the active ingredients in Salvia and Panax notoginseng to enter the tissues and organs of the body, with coronary artery dilation and analgesic effects, compound Danshen Dripping Pill has the advantage of dosage form, and the hydrophilic matrix helps the drug to be quickly dissolved and released, and it is very suitable for sublingual administration, and the active ingredients are directly absorbed into the blood through the mucosa when sublingual administration, which avoids the first-pass effect of the liver and the destruction of the drug by gastrointestinal digestive juices, improves bioavailability, and is conducive to rapid alleviation of the condition. Who is suitable to take Compound Danshen Dripping Pills?Today, Pharmacist Sun will introduce you one by one:
1.Coronary heart disease angina: compound Danshen dripping pill has the effects of lowering blood pressure, regulating blood lipids, anti-platelet aggregation, reducing myocardial oxygen consumption, improving myocardial energy metabolism, etc., can significantly improve the symptoms of coronary heart disease angina, significantly improve the ischemic performance of electrocardiogram, and can improve heart rate and blood pressure, improve the patient's exercise tolerance, suitable for long-term combination of patients with coronary heart pain angina on the basis of standardization, and can not tolerate nitroglycerin, isosorbide mononitrate and other nitrate drugs, the presence of aspirin or clopidogrel resistance, For patients with reduced exercise tolerance, compound Danshen Dripping Pill is a good supplement and combination drug, in addition, Compound Danshen Dripping Pill can also be used for first aid for angina pectoris of coronary heart disease. **For coronary heart disease, the conventional recommended dose of compound Danshen Dripping Pill is 10 capsules each time, 3 times a day, oral or sublingual, 28 days for 1 course of treatment, the taking time can be extended according to the condition, if the patient has stomach discomfort after taking the drug, it is recommended to take it sublingually or 30 minutes after a meal. For first aid, the conventional recommended dose of compound Danshen Dripping Pills is 10 capsules each time, taken sublingually, and if there is no relief after 5 minutes, another 10 capsules can be taken or nitrate drugs such as nitroglycerin can be changed.
2.Diabetic vascular disease: Compound Danshen Dripping Pill has the effects of anti-platelet aggregation, improving microcirculation, protecting cardiovascular system, reducing proteinuria excretion, etc., which can delay the occurrence and development of diabetic macrovascular disease, prevent and treat microangiopathy such as diabetic eye disease and diabetic nephropathy, and is a combined drug for the prevention and treatment of vascular complications on the basis of routine ** for diabetic patients. **In case of diabetic microvascular complications, the conventional recommended dose of Compound Danshen Dripping Pill is 10 20 capsules each time, 3 times a day, oral or sublingual, 24 weeks as a course of treatment, and the taking time can be extended according to the condition.
In terms of safety, Compound Danshen Dripping Pill has good cardiac safety, and when used in combination with antiplatelet drugs such as aspirin or clopidogrel, it will not increase the risk of bleeding, and only a few patients have nausea, belching, hiccups, abdominal pain, diarrhea, flatulence, stomach pain, stomach discomfort, acid reflux, dyspepsia and other digestive symptoms as well as headache, chest tightness, rash, dry mouth, flushing, excessive sweating, palpitations, Fatigue and other adverse reactions, and most of them can be resolved spontaneously, and long-term medication has good safety and tolerability.