We know that mesenchymal stem cells are both autologous and allogeneic;At this time, some fans are asking:Does the use of allogeneic stem cells affect our genes?
In response to this question, we answer it from two aspects.
First, stem cells don'tThe ability to alter the genes of other cells.
First of all, we need to understand that all cells in the human body cannot change the genes of other cells. Because each cell is a relatively independent individual, they can affect each other, but they can't change its genes. To give an inappropriate example, the human body is like an earth, and each cell is like a human being on the earth, and people are relatively independent from each other, in which a single individual can affect the thinking and appearance of another individual, but cannot affect the blood of another individual.
All the cellular genes in the human body are carriers of genetic information in our body, and they determine our characteristics and functions. Stem cell research mainly uses the regenerative ability of cells to develop diseases, and does not directly involve genetic alterations. As for real gene editing technology, that's another area.
Second, stem cells and the differentiated cells also die during metabolism.
First of all, stem cells and the cells they differentiate from do not exist all the time, they are also consumed by the body's metabolism. The metabolism of the human body has been carried out silently, after stem cells enter the human body, they will first enter the organs through the blood, on the one hand, they use a number of differentiation, paracrine, homing, immune regulation and other functions to play a role, and aging and death in a certain cycleIt will be gradually replaced by new endogenous tissue cells after completing its mission, and will not remain in the body for a long time. Therefore, stem cells do not have the potential to change genes.
Second, even if the amount of stem cells infused in a single infusion is large, it is only tens of millions, and it is impossible to compete with the 60 trillion cells of the autologous body. It's like a bowl of water poured into the sea, even if the bowl of water is ink, it disappears after blending into the vast sea.
Finally, at present, there are many mesenchymal stem cell research projects such as umbilical cord and placenta in stem cell clinics, and if they really change genes, then they may have been banned in the filing process as early as possible.
So, the reinfusion of stem cells does not affect our genes!Do you understand?