In the process of receiving consultations, we often encounter questions such as: Doctor, why is my embryo so good and still not implanting?
Currently, the pregnancy rate of IVF is about 50-60%. Therefore, when patients have gone through the painful process of stimulation and egg retrieval, and survived the long wait of 14 days after embryo transfer, not everyone can successfully conceive in one transfer. The failure of embryo implantation is a great blow to patients and also troubles medical workers. So, what are the reasons for the failure of implantation of high-quality embryos?
1. Chromosomal abnormalities
Some embryos are completely fine in appearance, and their appearance and growth are in line with the medical judgment of high-quality embryos, but they may have chromosomal abnormalities and such embryos often fail to implant successfully.
2. Uterine environmental problems.
For those with thin endometrium or uterine adhesions, uterine mediastinum, submucosal uterine fibroids, intrauterine adhesions and other adverse conditions, it will affect the endometrial environment, resulting in the difficulty of implantation of high-quality blastocysts.
3. Abnormal immunity.
For example, anticardiolipin antibody syndrome is a common immune disorder. In addition, if you carry certain antibodies, it may affect the development of the embryo.
4. Endocrine abnormalities.
Embryo implantation and continued development also depend on the coordination of the endocrine system, such as polycystic ovary syndrome, hyperinsulinemia, hyperandrogenism, hyperprolactinemia, thyroid dysfunction, etc., which can also lead to embryo implantation failure.
5. Coagulation abnormalities.
Embryo implantation depends on the blood of the endometrium**, and insufficient blood supply to the endometrium can cause the embryo implantation chance to decline, resulting in high-quality embryos not implanting.
Sixth, the impact of undesirable factors.
Long-term nervousness, fragility, anxiety and depression, long-term exposure to chemicals with strong odors, paints and formaldehyde in new houses, exposure to toxic chemicals, radiation, high temperature, etc. can affect the ability to conceive, and even cause fetal malformations or miscarriage. Therefore, it is recommended that families planning to become pregnant and those who are already pregnant should avoid exposure to adverse environmental factors.
5. Coagulation abnormalities.
Embryo implantation depends on the blood of the endometrium**, and insufficient blood supply to the endometrium will cause the embryo to implant to decrease, that is, to promote the non-implantation of 4AA high-quality blastocysts.
In short, the causes of implantation failure after high-quality embryo transfer are very complex, and individual differences are large, specific to a patient, doctors need to analyze the specific situation of the patient, find out personalized countermeasures, in order to improve the pregnancy outcome.
Therefore, it is not necessary to transfer high-quality embryos to be successful, and couples who are trying to conceive should face the good and bad after the transfer with the best attitude. Couples who choose IVF to conceive should also pay attention to recuperating their bodies and preparing for pregnancy scientifically, which can lay the foundation for the success of IVF.
At last. Best wishes to all mothers-to-be.
Get pregnant sooner.