Varicocele is a common urinary disorder in men with a high incidence and is one of the main causes of male infertility. So, why does varicocele jeopardize male fertility? This article will focus on the causes of varicocele that cause male infertility.
What is a varicocele?
Varicocele (VC) is a vascular lesionThe cranoid venous plexus in the spermatic cord causes venous reflux or poor reflux due to various reasons, resulting in abnormal dilation, elongation and tortuosity, which can lead to pain, discomfort and progressive ** dysfunction, which is one of the common causes of male infertility.
Research data show that the prevalence of varicocele in the general male population is 10% to 15%, in male primary infertility, the incidence of varicocele is 35% to 40%, and in male secondary infertility, it accounts for 70% to 80%.
What are the causes of male infertility due to varicocele?
First, the temperature increases
*Temperature increase is one of the important causes of male infertility caused by varicocele. When suffering from varicocele, the local temperature rises, because the optimal working temperature is usually 2-3 degrees below the body temperature, and this temperature increase can impair the spermatogenic ability.
2. Tissue hypoxia
Varicocele will lead to poor blood reflux, resulting in tissue hypoxia, affecting metabolism, and long-term hypoxic state will affect spermatogenic ability and affect sperm quantity and quality.
3. Endocrine dysfunction
The varicocele causes the temperature to rise, and the blood and oxygen supply are affected, which causes endocrine dysfunction in the interstitial cells in the seminiferous tubules, which affects the normal production and physiological function of sperm, resulting in infertility.
Fourth, the impact of toxic substances
When varicocele occurs, the blood of the renal vein and adrenal vein that has not undergone detoxification will reflux into the tissue, affecting the production and maturation of sperm, resulting in a decrease in sperm count, abnormal morphology, and dyskinesia in men, which in turn leads to male infertility.
5. Immune factors
Sperm itself has strong antigenicity, which can stimulate itself to produce anti-sperm antibodies (ASAB), which bind to sperm, so that sperm coagulates and affects its motility. When a man suffers from varicocele, the barrier and immune function of the blood testes are disrupted, and sperm enters the patient's bloodstream to produce ASAB, resulting in a decrease in sperm count and motility, which in turn affects fertility.
6. Infection
Varicocele can also trigger infection leading to inflammation, and long-term inflammatory stimulation can also impair spermatogenesis, negatively affecting sperm production and maturation.
Conclusion
In summary, varicocele causes male infertility due to a variety of factors, which can negatively affect sperm production and maturation. Therefore,If a man has symptoms of varicocele, he should seek medical attention promptlyto avoid permanent effects on fertility. Methods include medications, surgery, etc., and the specific regimen needs to be based on the specific situation of the patient. At the same time,It is important for patients who have been diagnosed with varicocele to understand the possible effects on fertilityThis helps to take effective measures in a timely manner and improve the success rate of childbirth.
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