If the water quality is not up to standard, the impact on the instrument:
1. The needle may be blocked and polluted;
2. The colorless and transparent water injection pipe may be discolored, and there will be impurities in it;
3. Cuvettes will be subject to wear and contamination;
4. The experimental analysis results are likely to exceed the standard.
What are the main effects of substandard water quality on the results of the biochemical instrument?
The specific manifestations are:
1. The impact of excessive ion content:
The most direct impact is that the ion content in plasma exceeds the standard, such as Mg2+, Ca2+, Fe3+, Cu2+, Zn2+ and other detection indicators, and will also affect the calibration of the project;
Because most of the metal ions are coenzyme factors, the excess of metal ions will directly affect the detection of enzyme activity; Excessive levels in water can lead to an increase in the measured values of these enzyme activity; (Many heavy metal ions have an inhibitory effect on enzymes, resulting in enzyme activity.)
Most anions will have a presence of cofactors for enzymes, which also have a certain impact on the determination of enzyme activity. (e.g., ci--amylase activates it);
The water with high ion content is likely to form crystals, resulting in the denaturation and attachment of protein organic matter to the pipeline, which will cause the pipeline of the biochemistry analyzer to be blocked, and the final measurement will be distorted; At the same time, it is also difficult to clean, and it will also accelerate the aging of the reaction cup.
2.Effects of organic matter:
The effect of organic matter is mainly reflected in the increase in the substance determination index. At the same time, the denaturation of organic matter adheres to the pipeline, which is also difficult to clean, and will also accelerate the aging of the reaction cup.
3.Effects of particulate matter:
Under normal circumstances, particulate matter cannot flow into the pipeline of the biochemical instrument through the pure water system, and the source is likely to be the secondary pollution of the water storage tank.
4.Microbial Influences:
The microbial removal work mainly relies on the pretreatment of raw water, and the ultrapure water machine is equipped with ultraviolet sterilization or terminal microfiltration to strengthen the removal of bacterial heat sources. But once the pretreatment enters the biochemistry analyzer pipeline, two things happen:
1) Microorganisms and products breed in the pipeline, causing the pipe to be blocked, and at the same time, the absorbance and blankness will also increase;
2) The effect of microbial enzyme production on the detection of instrument enzymes depends on the type of bacteria.
In order to ensure that the impact of water quality on the biochemical meter is minimized, we should take the following measures: establish a strict water quality testing system, regularly test the water quality, find and deal with water quality problems in time, and ensure that the water quality meets the standards.
Optimize the treatment process before the experiment, such as filtration, sedimentation, and disinfection of water quality, and reduce the influence of impurities, organic matter, and microorganisms in the water on the biochemical instrument.
Regularly maintain and clean the biochemical instrument to ensure the normal operation and service life of the instrument.
Regularly maintain and clean the biochemical instrument to ensure the normal operation and service life of the instrument.
Through the implementation of the above measures, we can effectively reduce the impact of water quality on the biochemical instrument, improve the accuracy and reliability of experimental results, and provide better services for medical treatment, scientific research and other fields.