Pregnancy and childbirth are high-risk periods for venous thromboembolism (VTE), which mothers are prone to venous thrombosis?
The development of VTE is associated with a number of risk factors, and the risk of VTE is significantly increased when physiologic changes during pregnancy and puerperium are combined with related risk factors. According to the characteristics of different risk factors, they are summarized into four categories:
1) History of VTE or VTE disease: including previous history of VTE, VTE that still exists after **, etc.; (2) There are comorbidities related to the onset of VTE: active autoimmune diseases such as systemic lupus erythematosus, antiphospholipid syndrome, etc., or inflammatory diseases, nephrotic syndrome, heart failure, type 1 diabetic nephropathy, sickle cell disease, malignant tumors, etc.; (3) Temporary risk factors: surgery during pregnancy, hyperemesis gravidarum, ovarian hyperstimulation syndrome, etc.; (4) Obstetric and other risk factors: family history of VTE, advanced pregnancy, multiple deliveries, obesity, paraplegia or prolonged bed immobilization, systemic infection, multiple pregnancy, preeclampsia, cesarean section, prolonged labor, stillbirth, severe postpartum hemorrhage or massive blood transfusion, etc. The occurrence of VTE is closely related to the number and degree of associated risk factors, and the more risk factors and the higher the degree of risk, the greater the risk of VTE. For those with the above high-risk factors, early prevention should be carried out.