What is toxoplasmosis.
Toxoplasmosis, also known as toxoplasmosis, is a zoonotic disease caused by the bacterium Toxoplasmosis gondii. Toxoplasma gondii infects almost all homeotherms, including humans, livestock, marine mammals, and wildlife, and is a zoonotic disease with a wide range of reservoirs. Felines are its definitive hosts, and other animals and humans are their intermediate hosts.
Source of toxoplasmosis infection.
Toxoplasmosis is transmitted to humans and animals infected with Toxoplasma gondii. Statistical analysis has shown that about 30% of the world's population may be infected with Toxoplasma gondii; About 79. Most of them are hidden.
Susceptible population. 
The population is generally susceptible. Infection can be caused by invasion by oocysts, trophozoites or cysts, and is more susceptible to slaughtering meat processors and medical personnel, pregnant women, fetuses, young children, and patients with immunosuppressed or malignant tumors.
Mode of transmission. There are two types: congenital transmission is when the fetus is infected from the mother in the womb, and the infection of a woman with Toxoplasma gondii during pregnancy can be transmitted to the fetus through the placenta. In addition, the fetus can become infected by ingesting amniotic fluid; Acquired transmission is mainly the invasion of pathogens into the human body through mucous membranes or injury**.
Specific modes of infection in humans.
ingestion of food or water contaminated with toxoplasma oocysts in cat feces;
ingestion of undercooked meat or meat products containing cysts;
The worm travels vertically across the placenta.
What are the clinical manifestations of toxoplasmosis.
After human infection with Toxoplasma gondii, it is usually in a state of hidden infection and does not show obvious clinical symptoms. However, it can cause secondary infections with weakened immunity, and in severe cases, death. Toxoplasma gondii usually causes chromosomal aberrations in humans, resulting in congenital malformations or birth defects; Causes neurological pathologies such as meningitis, cerebral palsy and epilepsy; causes intellectual developmental disability; Toxoplasmosis hepatitis presents with hepatosplenomegaly, cirrhosis of the liver, ascites, jaundice, etc.; It can lead to fertility disorders, miscarriages, stillbirths, etc., as well as progressive wasting of people.
The clinical manifestations of animals infected with Toxoplasma gondii are basically the same as those of humans: slow growth, reduced feed utilization, low production performance, long-term worm carrier, and death when severe; Causing serious economic losses such as abnormal abortions, stillbirths, and abnormal production of breeding animals.
How toxoplasmosis is.
For toxoplasmosis, there is currently no effective vaccine, and clinical ** mainly relies on drug-based chemistry** with the antimicrobial drugs sulfadiazine, spiramycin and clindamycin or the antimalarial drugs pyrimethamine and atovaquone. For the toxoplasmosis of various livestock and poultry, the principle of "prevention first, supplemented by supplementation" is mostly adopted, and sulfonamides are also used more.
How to prevent toxoplasmosis.
How to prevent toxoplasmosis in humans:
First of all, try not to contact animals suspected of having toxoplasmosis, pay attention to the meat must be thoroughly processed and cooked when eating, and pregnant women should try not to raise cats, dogs and other animals. Try not to touch the feces of animals such as cats to avoid infection. In addition, pregnant women should have regular check-ups for toxoplasmosis to avoid the occurrence of congenital toxoplasmosis.
How to prevent toxoplasmosis in animals:
Cats are forbidden to enter the barn to prevent cat feces from contaminating the feed and drinking water of the barn.
Do a good job of rodent prevention and rodent control in the barn.
Aborted fetuses and excreta also contain trophozoites and should be strictly disinfected.
The barn should be kept clean and disinfected regularly.
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