Product name: PCL(3K)-PEG(5K)-NH2 polycaprolactone polyethylene glycol amino.
PCL(3K)-PEG(5K)-NH2 is a polymer composed of polycaprolactone (PCL), polyethylene glycol (PEG), and amino (NH2) derivatives.
PCL (3K) refers to polycaprolactone with a molecular weight of about 3 thousand daltons (KDA). PCL is a biodegradable polymer with good degradability and biocompatibility.
PEG (5K) refers to polyethylene glycol with a molecular weight of about 5,000 daltons (KDA). PEG has good water solubility and biocompatibility, and is commonly used as a carrier or modifier in drug delivery systems.
NH2 is an amino group and is an active chemical functional group that can participate in chemical reactions or react with other molecules.
PCL(3K)-PEG(5K)-NH2 polymers combine the biodegradability of PCL, the water solubility and biocompatibility of PEG, and the chemical reactivity of NH2. NH2 functional groups enable polymers to be further chemically modified, and can undergo condensation reactions and coupling reactions with other functional groups to regulate the properties and applications of polymers. This polymer can be used to prepare carrier materials such as nanoparticles, microcapsules, or scaffolds for drug delivery, tissue engineering, and biomedical applications.
Amino (NH2) is a functional group also known as an amine group. It consists of one nitrogen atom and two hydrogen atoms and is a basic building block in chemistry. Amino groups are ubiquitous in many organic compounds and biomolecules and have important chemical and biological functions.
In chemistry, amino groups usually react with other functional groups to form new compounds. For example, an amino group can undergo an amide condensation reaction with a carboxyl group to form an amide; or condensation reaction with aldehydes or ketones to form amines. Amino groups can also undergo an amidation reaction with acids, chlorides or anhydrides, etc., to form amides.
In biology, amino groups are one of the building blocks of biological macromolecules such as proteins and nucleic acids. Amino groups are the basic building blocks of amino acids in proteins, while they are the basic building blocks of bases in nucleic acids. The chemical properties and spatial structure of amino groups play an important role in the function of biomolecules, such as determining the folding structure of proteins and the specificity of active sites.
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: Qi Yue Hao February 21, 2024.