Statistics show that about half of the adults in China are overweight, and the resulting health problems deserve our attention. Obesity can bring a variety of health problems. In addition to the common three highs, such as hypertension, hyperlipidemia and hyperglycemia, many friends with obesity problems are also plagued by the "fourth high". This "fourth highest" is the problem of high uric acid.
The full name for hyperuricemia is "hyperuricemia". Like hypertension, hyperlipidemia, and other problems, it is a common chronic metabolic disease, and it is considered hyperuricemia in men and menopausal women with a uric acid concentration of more than 420 mol and more than 360 mol l in women.
While these problems may not be painful and there are no symptoms of physical discomfort, this "metabolic syndrome" problem will gradually take a toll on many aspects of health. For friends with high uric acid problems, understand the relevant knowledge of high uric acid, actively control the health status of high uric acid, and maintain the health of high uric acid for a long time.
Reacquaint yourself with high uric acid
Uric acid is a metabolite in our body, mainly from the oxidation of nucleotides in the metabolic process of autologous cells and the oxidative conversion of purine substances ingested externally. In terms of physiological function, uric acid in the blood is not useless.
Studies have shown that uric acid in the blood has a certain antioxidant effect and has a certain effect on maintaining normal blood pressure. Therefore, when the level of uric acid in the blood is in the normal range, uric acid is actually an antioxidant that protects blood vessels from damage caused by oxidative reactions. This is a veritable "good thing".
No matter how good things are, so is uric acid. Uric acid is a slightly soluble substance. If the concentration in the blood exceeds a certain level (blood uric acid concentration exceeds 382 mol l), when supersaturated is reached, the crystals of individual urate precipitate in the blood, and it is these precipitated urate crystals that are the "culprit" of the health hazards of high uric acid.
Gout caused by high uric acid, kidney health hazards, vascular health hazards, and related tissue and organ hazards caused by tophi are all caused by urate crystals. In order to avoid these health risk problems, it is very important to actively control uric acid for friends with high uric acid problems.
Is it true that the faster you lower uric acid, the better?
When some friends find out that they have a high uric acid problem, they hope that they can't immediately lower it to 0, but in fact, this is an unrealistic and unscientific way to lower uric acid. Under the influence of a variety of factors, high uric acid is gradually formed, and the method of ultimately lowering uric acid is not advisable. We say that active control of uric acid does not mean a rapid reduction of high uric acid, but that a rational and scientific approach should be taken to strengthen the control of high uric acid.
Why is controlling high uric acid not fast? First of all, friends who usually have high uric acid problems will have a certain amount of urate deposition in their bodies. When urate levels in the blood drop, these deposited urate are gradually dissolved back into the bloodstream, reducing the associated health risks.
However, if uric acid is lowered too quickly, crystals deposited in joints and other areas will be greatly disturbed. This rapidly fluctuating change induces an acute inflammatory response in the body. Many friends use medications to lower uric acid. If the dose is too large, or if various uric acid-lowering drugs are taken at the same time to lower uric acid quickly, it may cause uric acid to be lowered too quickly.
Uric acid drops too fast. Many people also take drugs that promote the excretion of uric acid by the kidneys to lower uric acid. During renal excretion, it is inevitable that more urate will be deposited in the kidneys.
In this case, if we do not pay attention to the alkalinization of urine, we can also control the rate at which uric acid is excreted, which can lead to the formation of urate stones in the kidneys and carry the risk of acute damage to the kidneys.
In addition, some friends like to lower uric acid too low, thinking that the lower the uric acid, the better, which is also a cognitive misunderstanding. As we said earlier, a healthy level of uric acid has certain physiological functions that are beneficial for health. Therefore, when lowering uric acid, the range of uric acid reduction should be controlled as much as possible, and the uric acid concentration should not be less than 180 mol l.
In fact, in most cases, when it comes to controlling uric acid, people who don't have a gout attack can lower their uric acid to less than 360 mol L, and those who have gout reversals can control uric acid below 300, which is a good level, especially for those who take medications to lower uric acid. Minimizing the amount of medication under the premise of controlling to a safe level is also an important aspect of ensuring drug safety. There is no need to use large doses to excessively lower uric acid.