6-Nitroresveratraldehyde (CAS: 20357-25-9), with the chemical formula C8H7NO5, is a yellow crystalline solid. Its physical properties include a melting point of 90-91 °C, a boiling point of 305 °C, and a molecular weight of 19715g mol with a density of 145g/cm³。The chemical properties are characterized by aldehyde and nitro functional groups, which have certain activity.
The main synthesis route of 6-nitroresveratraldehyde is prepared by esterification reaction of nitrobenzoic acid with veratraldehyde under alkaline conditions. The synthesis route is simple and efficient, with high yield, and is suitable for industrial production.
The method for preparing 6-nitroresveratraldehyde includes adding nitrobenzoic acid to glacial acetic acid, then adding sodium hydroxide and veratraldehyde, washing with water after the reaction, and vacuum drying to obtain the product. The method is simple to operate and suitable for laboratory-scale preparation.
As an intermediate in organic synthesis, 6-nitroresveratraldehyde is widely used in pesticides, pharmaceuticals and dyes. Its derivatives have antibacterial, antioxidant and other biological activities, and are an important intermediate compound.
Microchannel technology is increasingly widely used in the field of organic synthesis, and it also has great potential for the synthesis of 6-nitroresveratraldehyde. Through the microchannel reactor, rapid mixing and efficient conversion of reactants can be realized, and the selectivity and yield of the reaction can be improved. In the future, with the continuous development of microchannel technology, the production of 6-nitroresveratraldehyde will be more efficient and environmentally friendly.
In summary, 6-nitroresveratraldehyde, as an important intermediate in organic synthesis, has a wide range of application prospects in the fields of pesticides, pharmaceuticals and dyes. The development of microchannel continuous technology will further promote the optimization and improvement of its production process. Future research can focus on the design and application of microchannel reactors to achieve efficient synthesis and industrial production of 6-nitroresveratraldehyde.