Traditional medical models are often designed based on the general symptoms of the disease, but the same approach does not work for everyone. The Third Drug Revolution, also known as:The personalized medicine revolution, based on advances in modern genomics and bioinformatics, opens up entirely new possibilities for drug discovery and medicine**.
Tailor the dosing regimen to the patientYesPersonalized medicineAn important part of itSerum drug levels are monitoredAn important part of achieving precision medicine.
Serum drug levels are monitoredIt refers to the assessment of the metabolism and efficacy of a drug in the body by regularly measuring the blood concentration level of a specific drug in the patient's body. Monitoring of blood levels can help doctorsAdjust the dosage of the drug and give it an individualized strategyto achieve better results while avoiding or reducing unnecessary results
Blood concentration monitoring has a variety of applications in clinical practice. For example:
InHeart disease or high blood pressureIn cases where it is necessary to maintain a stable drug concentration in the blood, blood drug concentration monitoring can help determine whether the drug dose is appropriate and make an individualized dose adjustment;
InAnti-cancer**In order to avoid excessive concentration of chemotherapy drugs from damaging normal tissue cells, monitoring blood drug concentrations can help doctors to individualize the design of the best regimen;
Regular monitoring of plasma concentrations in organ transplant patients after 2 months** can reduce the incidence of drug toxicity and graft rejection.
Psychotropic medications such as antidepressantsIt is often narrow in the safety range and strong in adverse reactions, so it is necessary to detect the blood concentration in clinical practice, adjust the type and dose of the drug in time, and ensure the safety and reasonableness of the drug.
Antifungal drugsThe blood concentration of antifungal drugs should be tested to formulate a more appropriate dosing regimen to ensure the effectiveness and safety of the efficacy.
In addition, for patients with liver, kidney, heart, gastrointestinal and other diseases, poor long-term medication compliance, and clinical conditions such as co-medication interactions, it is often necessary to use blood drug concentration monitoring to ensure the rational use of drugs by patients.