Refuting rumors丨Is blood transfusion between relatives safer? Wrong, the lethality rate is even high

Mondo Social Updated on 2024-02-02

Imagine a family gathering where everyone is sitting around discussing health topics, and suddenly someone mentions: "If I need a blood transfusion one day, I will choose my relatives, because blood is familiar and definitely safer." ”

This may sound reasonable, but who doesn't want to rely on their family in times of crisis? However, medical research and practice tell us that this intuitive thinking may be leading us to a serious misunderstanding.

Actual situation

Many people believe that kin-to-family blood transfusions are safer than receiving blood from strangers, because they believe that genetic similarity means that blood is also more compatible. However, this is a common misconception. Blood compatibility is not determined by genetic similarity, but by blood type and other blood characteristics. Even between relatives, if the blood type and Rh factor do not match, a blood transfusion can still lead to a serious immune response.

Medical basis

The key to the safety of blood transfusion lies in matching blood groups. Human blood types are divided into A, B, AB, and O, as well as positive and negative factors for the Rh factor。Even if it is an immediate family member, their blood type may be different. If this is ignored during transfusion, even inter-relative transfusions can lead to acute hemolytic reactions, a serious immune response that can be fatal to the recipient.

Immunological perspective

From an immunological point of view, there are antigenic differences, even between relatives. These differences can cause the recipient's immune system to respond by producing antibodies that attack the transfused bloodstream. Especially in close relatives, the similarity of certain antigens can lead to confusion and overreaction of the immune system, which in turn increases the risk of serious complications.

Risk of genetic disorders

Kin-to-family blood transfusions may also increase the risk of certain genetic disorders. For example, genetic disorders such as thalassemia may be more common in families. Without detailed blood screening, these conditions may go unnoticed during blood transfusions between relatives, posing additional health risks to recipients.

Kin-to-family blood transfusions are not always a safer option. Medical professionals consider blood type, Rh factor, and other blood characteristics when performing blood transfusions to ensure the safety of blood transfusions. Blood between relatives may be at higher risk due to individual differences. Therefore, regardless of whether the transfuse is a relative or not, rigorous blood matching and screening is key to ensuring safe transfusions.

In the medical field, kin-to-family blood transfusions may seem like a natural and safe option, but this is a common myth. For example, the family of a patient with severe anemia is desperate to be rescued by a blood transfusion from an immediate family member. However, the truth is that blood transfusions between relatives are not always safer and may even increase certain health risks. In this case, the patient received his brother's blood, but unfortunately immune rejection occurred, leading to serious complications. This example illustrates that even blood from relatives can cause adverse reactions due to immune factors and genetic differences.

Blood transfusion safety measures: Make sure the blood is compatible

To ensure the safety of blood transfusions, the following measures are essential:

Blood type and RH factor match:Blood type (A, B, AB, O) and Rh factor (positive or negative) must be closely matched. Even between relatives, a mismatch of blood groups can lead to serious transfusion reactions.

Cross-matching test:This test is used to determine if there is an incompatibility between the recipient's blood and the donor's blood. This step must be carried out even between relatives.

Screening for infection: All blood donors must undergo rigorous screening for pathogens, including but not limited to HIV, hepatitis B, and C viruses.

Immunological tests:In particular, in the case of inter-relative blood transfusions, additional testing for antibodies and leukocyte antigens is required to reduce the risk of immune rejection.

The implementation of these measures can greatly reduce the risks during blood transfusion and ensure patient safety. Even when blood transfusions are performed between relatives, the same strict standards and procedures must be adhered to. In this way, we can improve the safety of blood transfusions while reducing unnecessary health risks.

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