Aunt Lin, a kind old man who was over the age of six, suffered a sudden toothache not long ago. The intense pain, like a merciless beast, tore at her body and mind fiercely. At first, Aunt Lin didn't take this small toothache to heart, until the pain became unbearable, and then went to the health center to seek treatment. The doctor prescribed two painkillers and carefully instructed the dosage of the medication. However, a few days passed, and Aunt Lin's toothache was not relieved. With nothing to do, Aunt Lin took out a dose of anti-inflammatory medicine from the medicine box at home, hoping to use it to ** her pain. 
To Aunt Lin's surprise, the decision to mix these three medicines together almost made the fire of her life almost extinguished. In just two days, Aunt Lin's urination frequency decreased sharply, and her feet were inexplicably swollen. When I went to the hospital, I found that the urine contained protein, and I was diagnosed with acute renal failure. After the doctor's in-depth understanding, Aunt Lin's ** was finally confirmed - that is, she mixed the three medicines together and took them. What is even more shocking is that the drug she later took has not long ago been listed as a restricted use. Doctors solemnly warn that all four drugs have been restricted, but they are the ones that many families have on hand. 1. Vitamin C Yinqiao Tablets Vitamin C Yinqiao Tablets were once known as the best cold"Miracle medicine", the glow of its peak is unforgettable. In the eyes of many people, it is a unique blend of traditional Chinese medicine formula and vitamin C. However, Vitamin C Yinqiao Tablets is not a simple Chinese medicine or Western medicine, but a unique combination of Chinese and Western preparations. It has the advantage of mild**cold, but its disadvantages are just as obvious. Due to the differences in the prescription ratio and dosage ratio of Chinese and Western medicines in various pharmaceutical factories, the quality of drugs of different brands is uneven, which undoubtedly increases the risk of using vitamin C Yinqiao tablets. According to the Adverse Drug Reaction Information Circular issued by the National Medical Products Administration, from 2004 to 2010, the National Adverse Drug Reaction Monitoring Center received a total of 1,885 case reports on vitamin C Yinqiao tablets. These adverse events involve the central and peripheral nervous system, the digestive system, and** its appendages. Of these, 48 were severe cases, accounting for about 2 of all reports55%。Therefore, for safety reasons, the application of vitamin C silver warp tablets has been limited to a certain extent. Despite this, vitamin C tablets are still available in pharmacies and hospitals, but caution is recommended for colds unless necessary**. Second, compound licorice tablets mention **cough"Miracle medicine", people often think of compound licorice tablets. This essential medicine for the family not only has a rapid effect and a remarkable cough suppressant effect, but also is close to the people and has become the first choice for the people to treat cough. However, this one is widely popular"Miracle medicine"But it has been subject to many constraints. As early as 2005, compound licorice tablets were confirmed as prescription drugs and should be purchased and used according to the doctor's instructions. In 2014, compound licorice tablets were found to contain illegal ingredients specified by the U.S. National Drug Administration. In 2020, the State Food and Drug Administration issued the "Announcement on Revising the Instructions of Compound Licorice Tablets", which revised the instructions and clarified the specific scope and dosage of their use. In addition to the safety issues mentioned above, compound licorice tablets also have the major hidden danger of addiction. Clinical studies have shown that long-term use of compound licorice tablets may lead to a certain degree of dependence and addiction. The withdrawal reaction is strong after abrupt discontinuation of the drug, and it takes 2 to 3 months to return to normal. In addition, long-term overdose of compound licorice tablets may also cause pseudoaldosteronism, which is a secondary hypertension characterized by increased blood pressure, low blood potassium, metabolic alkalosis, etc. In order to ensure good health, infants, the elderly, patients with peptic ulcers, diabetes and hypertension should not use compound licorice tablets. Other people should also take the drug under the guidance of a physician, and the medication cycle should not exceed 1 week. 
3. Nimesulide, a non-steroidal anti-inflammatory drug, has a wide range of dosage forms in the market, including tablets, dispersible tablets, sustained-release tablets, oral disintegrating tablets, capsules, granules, dry suspensions and gels. However, its functions are not limited to anti-inflammatory, analgesic and antipyretic, and many doctors and even patients mistakenly believe that it can be used as a medicine for fever**. As a result, nimesulide was once widely used for fever**, both in children and in children. However, Nimesulide is not completely safe. Its most common adverse effects include gastrointestinal reactions such as nausea, vomiting, and abdominal pain. In addition, domestic and foreign adverse drug reaction monitoring has found that nimesulide may cause allergies, coagulation dysfunction, leukopenia, liver and kidney function impairment and other problems. In order to ensure public safety, the Medicines Administration has implemented a series of risk management measures to limit the scope of application of nimesulide, positioning it as a second-line drug for symptoms such as acute pain, painful osteoarthritis and primary dysmenorrhea. At the same time, it is clearly stated that the use of this drug is prohibited in children under 12 years of age. After the introduction of this regulation, the commonly used high-fever antipyretic drug Ruizhiqing has been withdrawn from the market, and replaced by safer fever-reducing drugs such as ibuprofen and acetaminophen. In 2011, the State Food and Drug Administration also issued the "Notice on Strengthening the Administration of the Use of Nimesulide Oral Preparations", which clearly stipulates that children under the age of 12 should not use nimesulide as a fever reducer; This drug is only suitable for diseases such as arthritis and should only be considered if other non-steroidal anti-inflammatory drugs are ineffective; And the dosage used is strictly regulated. 4. Ribavirin, also known as "virazole", its metabolites can be used as competitive inhibitors of viral synthase to block viral replication and diffusion, and are broad-spectrum nucleoside antiviral drugs. This has led many people to mistakenly believe that it fights all viruses and thus is used as a standing remedy for colds. However, colds are mostly caused by rhinovirus, coronavirus, parainfluenza virus, adenovirus and enterovirus infection, while ribavirin mainly targets respiratory syncytial virus and covers only about half of these virus species. Therefore, ribavirin is not suitable as a common cold medicine. What's more, pregnant women should absolutely contradict ribavirin! The National Adverse Drug Reaction Information Bulletin has warned of the safety risks of ribavirin, including the possibility of fetal abnormalities, malformations, tumors and hemolytic anemia. Based on human clinical data, the birth defect rate was as high as 9 in 88 live births born to pregnant women who were directly exposed to ribavirin09%, much higher than 272% background neonatal birth defect rate. On the basis of this, although ribavirin, a powerful antiviral drug, has a significant efficacy, its effectiveness cannot be ignored. Therefore, children under 3 years of age are prohibited from using it, otherwise it may seriously affect their growth and development. In addition, phenacetin has strong renal toxicity in antipyretic and analgesic, and once the dosage is too large, it may lead to papillary necrosis, uremia, acute renal failure, and even induce renal pelvic cancer and bladder cancer. Therefore, it is essential to use the medication safely under the guidance of a medical professional. To sum up, these 5 medicines that are commonly used for colds** actually have great potential dangers. In order to reduce its harm, the NMPA has established a series of medication restrictions and requires the purchase and use under the guidance of professional physicians. Of course, we must also learn to use drugs safely in our daily lives and avoid drug risks. Before using any medicine, be sure to read the drug label carefully and carefully to understand the contraindications. At the same time, when taking the drug, it must be strictly in accordance with the recommended dosage on the instructions, and the dosage of the drug cannot be reduced or increased without authorization. If you need to adjust the dose, it is important to do so under the advice and guidance of a medical professional. 
In addition, we cannot arbitrarily stack or mix drugs, especially wind-heat detoxification drugs. These drugs usually contain a variety of components, and most of them are hepatorenal toxic. If the combined use results in excessive doses, it can be life-threatening. Therefore, we need to check the medicine preparation box at home frequently to ensure that the medicine has not expired. Once you find that the medicine is expired, you should replace it in time, and do not use the expired medicine because you are worried about waste. At the same time, we should not consume medicines as health products, let alone abuse drugs to prevent and cure diseases without getting sick. Casual medication may lead to more problems. In response to the above content, you can speak freely in the comment area and share your views and opinions. Let's work together to learn how to use medicines safely and effectively to protect our health. February** Dynamic Incentive Program