Structural characteristics of CHEK1 recombinant protein

Mondo Science Updated on 2024-02-22

Introduction:

CHEK1 is an important protein kinase that is widely involved in cell life cycle regulation and DNA damage repair. Its recombinant protein is widely used as an important biomedical research tool. In this article, we will provide a comprehensive introduction to the structure, function, mechanism of action and potential applications of CHEK1 recombinant protein in biology.

Catalog No. PA1000-7502

Structural characteristics: CHEK1 protein includes N-terminal domains, kinase domains, and C-terminal regulatory domains that are highly conserved among different species. Its domain specifically recognizes DNA damage signals and interacts with other proteins to regulate the cell cycle and DNA repair.

Functional mechanism: CHEK1 regulates the cell life cycle mainly by phosphorylating substrate proteins. When cellular DNA is damaged, CHEK1 is activated, which stops cell circulation by activating cell cycle regulatory proteins, thereby enhancing DNA repair. In addition, CHEK1 is also involved in the regulation of cellular filament**, ensuring that chromosomes are properly separated.

Biology Function:

CHEK1 plays an integral role in biological processes. Studies have shown that CHEK1 deletion or abnormality may lead to a decrease in the ability of cells to repair DNA damage. Therefore, CHEK1 has always been regarded as a potential ** target, and CHEK1 recombinant protein has also been widely used in research.

Potential applications: The CHEK1 recombinant protein not only plays an important role in cancer research, but also has a wide range of applications in other disease fields. For example, recent studies have shown that CHEK1 may also play a role in neurodegenerative diseases, so the CHEK1 recombinant protein may be a new pathway for these diseases.

Conclusion: In conclusion, CHEK1 recombinant protein plays an important role in cell cycle regulation and DNA repair as an important biological research tool. The in-depth study of its structural characteristics and functional mechanisms will not only help us better understand the regulatory mechanism of cellular life activities, but also provide new ideas and pathways for related diseases.

Through a comprehensive introduction to the recombinant CHEK1 protein and the analysis of its biological functions, we have a deeper understanding of this important protein and its potential applications, laying a solid foundation for future biological research and clinical **. The study of CHEK1 recombinant protein will continue to bring more possibilities for us to unravel the mysteries of life activities.

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