Recently, MedCity News reported on the clinical progress of Galapagos using Lonza's Cocoon platform to manufacture two cell-based** drug candidates for point-of-care drug delivery.
A key challenge in CAR-T** is patient waiting time. CAR-T cells are usually produced in a laboratory far away from the hospital, where transportation and production time result in a waiting time of up to a month or more.
GalapaGons aims to shorten time and improve patient access through cell** technology manufactured on-site in hospitals where patients receive**. At last month's American Society of Hematology (ASH) Annual Meeting, Galapagos reported recent clinical data from the two cells**, showing that its technology is able to produce CAR-T** in seven days and exhibits highly anticipated response rates. GALAPAGOS Enables On-Site Manufacturing in Hospitals The technology platform for point-of-care drug delivery is Lonza's Cocoon fully enclosed, automated cell** production platform, which allows real-time remote monitoring of the production process through a software system. *
The Cocoon platform is a flexible, functionally closed, highly customizable, scalable, end-to-end cell production platform with fewer touchpoints and higher quality products.
End-to-end automation.
Integrate multiple steps to obtain an automated system for complete cell processing, including protocols for cell isolation, activation, transduction, transfection, expansion, and harvesting.
Closed system and integrated consumables.
Designed to minimize touchpoints and cleanroom space requirements. Improve product quality and process efficiency by reducing the risk of human error and cleanroom requirements.
Dual-temperature controlled environmental unit.
37 °C and 4 °C
User-friendly state-of-the-art software.
Editable for simple on-site customization. PH DO is monitored and can be fed back in real time; The process can be adjusted automatically.
Flexible. It can be integrated with LONZA's 4D Nucleofector LV electroporation system or used for viral transfection.
The products described herein are not medical devices or can be directly used for human diagnostic purposes, they are only for scientific research or production purposes, and no express or implied warranty is given as to the use of the products herein, and it is up to the user to determine their suitability for the intended process or purpose.