In the context of inflammatory diseases, Helicobacter pylori infection, gastric acid hypersecretion, and disruption of the gastric mucosal barrier are the three most common causes that may contribute to the development of gastroduodenal disease.
First of all, Helicobacter pylori infection is one of the main triggers of chronic gastritis, a condition that increases the risk of antral inflammation and stomach ulcers. Over time, this infection can lead to the formation of duodenal ulcers. Helicobacter pylori can cause disease on the basis of gastritis and, if not promptly**, may form a severe duodenal ulcer in the later stage.
Secondly, hypersecretion of gastric acid is closely related to the onset of duodenitis. Long-term exposure to high gastric acid may cause atrophy, thinning, and a decrease in the number of glands in the epithelial cells of the gastric mucosa, which can lead to atrophic gastritis. This condition not only causes damage to the gastric mucosa, but may also increase the risk of gastroduodenal ulcers.
Finally, the disruption of the gastric mucosal barrier is another key factor that leads to ulcer formation. When the gastric mucosal barrier is damaged due to excessive secretion of stomach acid and pepsin, or when the gastric mucosal barrier is damaged due to Helicobacter pylori infection or genetic factors, fluid from the digestive tract may leak into the stomach and cause ulcers. This disruption of the gastric mucosal barrier not only leads to the formation of ulcers, but can also aggravate the degree of inflammation.
In order to prevent and ** gastroduodenal disease, we need to take corresponding strategies against these factors, such as completely ** Helicobacter pylori, regulating gastric acid secretion, protecting the gastric mucosal barrier, etc. In addition, maintaining healthy lifestyle and eating habits is also key to preventing these diseases. This includes eating right, exercising moderately, reducing stress, and avoiding overexertion. Only through comprehensive and preventive measures can we effectively control and improve the quality of life of patients.