Osteoarthritis is a chronic condition that causes joint pain and stiffness. The knee, hip, and hand facets are most affected. It can have a significant impact on quality of life and knee function. Chronic pain makes it difficult for people to move, such as walking and going up and down stairs. And the disease can't**. It can only rely on drugs or occlusion to delay the development, and in severe cases, only artificial knee replacement can be performed
* It has a regulatory effect on the human immune system, as early as the nineties of the last century, doctors used **injections to**rheumatoid arthritis, the main ingredients are gold salts (gold nofen and sodium thiomalate), gold salts are known for their immunosuppressive and anti-inflammatory effects, it inhibits the activity of an enzyme called adenylyl cyclase in immune cells, blocking the action of pro-inflammatory substances. However, adverse effects have been reported after injection, and doctors gradually do not take this **, but replace it with methotrexate, hyaluronic acid, platelet-rich plasma, and placental tissue matrix.
With the update of technology, there is now a new *** different from the previous ** rheumatoid arthritis dmard gold, the new technology is much less risk of infection and is a regenerative technology that activates existing local stem cells and supports their differentiation, using the patient's own blood combined with specially designed gold particles (gold acts as a catalyst for blood cells to produce important cytokines), thus triggering anti-inflammatory and regenerative processes, gold refers to 99Tiny particles of 99% gold, usually 20 milligrams, are injected directly into the affected joint.
*Can activate cytokines, which are small proteins that, when released into the body, prompt the immune system to do its job. These cytokines can be activated to send a stronger message to the immune system. In other words, the specially formulated gold particles are mixed with a person's blood to produce living cytokines, which are injected back into the body to not only repair and regenerate tissues, but also reduce swelling, pain, and inflammation.
Doctors take a small sample of blood from the patient.
The blood is mixed with selected gold particles in a special tube, taking care that the shape, number, surface, concentration and size of the gold particles play a decisive role.
The mixture is incubated for 24 h to allow a reaction between the blood fluid and gold.
The mixture is spun rapidly in a machine, the mixture is centrifuged, and gold, platelets, and blood cells are separated from the serum. The fluid is rich in cytokines and growth factors that are produced specifically for the patient. In this process, the patient's own regenerative factors (cytokines and various growth factors) are filtered and concentrated.
Doctors inject this serum into the affected area, such as the affected joints, tendons, or tissues, without the need for additional ingredients. It is usually given 4 injections in 2-4 weeks.
Because the technology is still forward-looking, it is still in the clinical trial stageMay only be effective in a subset of patients, with half of patients improving early in the course of the disease, according to a study of 30 patients with knee osteoarthritis, 22 of whom experienced improved symptoms, and most patients experienced pain relief within 6-8 weeks of the disease. In another study, 9 out of 64 patients** failed, with a mean failure time of 32 months.
When to consider ***
*Particles interact with the body's immune system, stimulating the release of substances to block pain and inflammatory pathways, and how many ionic complexes are released from the particles depends on the level of inflammation. The new *** can be used for **rheumatoid arthritis and osteoarthritis. And the sooner the treatment, the best effect, but it is not necessarily effective for all patients, and it is still somewhat inconvenient and somehow ***, so only when other conservative *** are ineffective, should it be considered that *** has the potential to improve joint pain, function and stiffness.
Because it is a new **, the effect is good for time research, and it is possible to relieve the pain of arthritis in patients for a long time. However, it is difficult to guarantee whether it can play the role of knee replacement.
Medical science, for reference only:
Reference: Gold Particles ** Knee Osteoarthritis, European J Pain, 2022
Clinical Study of Intra-articular Gold-Induced Cytokine Injection** in Patients With Osteoarthritis of the Knee Joint", Clinical Trial, 2021
New Injections for Knee Pain in Mexico, Medical Tourism Inc., 2021