Polyethylene glycol, disulfide bonds, polylactic acid hydroxyacetic acid copolymer, maleimide

Mondo Health Updated on 2024-02-01

Product name: Polyethylene glycol-disulfide bond-polylactic acid hydroxyacetic acid copolymer-maleimide.

Product Name: plga-peg-ss-mal

Polyethylene glycol-disulfide-polylactic acid hydroxyacetic acid copolymer-maleimide (PLGA-PEG-SS-MAL) is a new type of biodegradable polymer material with excellent biocompatibility and degradability. This material has a wide range of applications in the fields of drug delivery, genetics**, tissue engineering, and regenerative medicine.

The synthesis of PLGA-peg-SS-mal is obtained by linking polylactic acid hydroxyacetic acid copolymer (PLGA) with polyethylene glycol (PEG) through a disulfide bond and then reacting with maleimide. The synthesis method of this material has the advantages of simple operation, mild conditions and high product purity.

PLGA-PEG-SS-MAL has good biocompatibility and degradability, and can be gradually degraded in vivo and metabolically excreted by the body. This material does not cause obvious inflammatory reactions and immune rejection reactions in the body, and has little damage to the body, which can meet the needs of drug delivery and tissue engineering.

In addition, PLGA-PEG-SS-MAL also has good drug release performance and target localization ability. By adjusting the composition and structure of the material, the sustained release and targeted delivery of the drug can be realized, and the efficacy of the drug can be improved and reduced.

In conclusion, PLGA-PEG-SS-MAL is a new type of biodegradable polymer material with wide application prospects. Its synthesis method is simple, the conditions are mild, the product purity is high, and it has good biocompatibility and degradability, which can meet the needs of drug delivery, genetics, tissue engineering and regenerative medicine. With the deepening of research, this material will play a more important role in the biomedical field in the future.

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Editor: Qi Yuehao, January 10, 2024.

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