The medicinal herbs of Nine-mile are the dried leaves and leafy shoots of the Rutaceae family plants Nine-mile and Thyme. The name of Jiulixiang first appeared in the Ming Dynasty, because of its flower smell and aromatic by the folk in the Lingnan area called "Jiulixiang", plant taxonomists will be Jiulixiang and Thyme are divided into the genus Jiulixiang in the Rutaceae family. Modern pharmacological research shows that Jiulixiang has anti-inflammatory and analgesic, anti-tumor, hypoglycemic, anti-insect and antibacterial, prevention of osteoporosis, anti-fertility, anti-oxidation and other effects, and is clinically mostly used for chronic gastritis and other inflammatory diseases.
This article only makes some brief analysis from the perspectives of the origin, characteristics, quality, origin, efficacy, and product application of Jiulixiang.
One herb per issue
One
Primordial
This product is a Rutaceae plant Murraya exotica Land thyme murraya paniculata (LJack's dried leaves and twigs with leaves. It can be harvested all year round, with the old branches removed and dried in the shade.
II
traits
Nine mileThe shoots are cylindrical in shape and 1 5 mm in diameter. The surface is grayish-brown with longitudinal wrinkles. The quality is tough, not easy to break, and the section is uneven. pinnate compound leaves with 3 9 leaflets, mostly detached; The leaflets are obovate or nearly rhomboid, the widest point is above the middle, about 3 cm long and about 1 cm wide5cm；apex obtuse, acutely pointed or concave, base slightly oblique, entire; Yellowish-green, thin leathery, with hyaline glandular spots on the upper surface, petioles short or nearly sessile, sometimes pubescent on the lower part. It is fragrant, bitter and pungent, and has a numb tongue feeling.
ThymeThe leaflets are ovate or elliptic, widest in the middle or below, 2 8 cm long and 1 3 cm wide, with an apex acutely or short-pointed.
Medicinal material trait diagram
Source**: Hong Kong Baptist University Chinese Materia Medica Image Database.
Three
Quality
It is better to have many leaves, green color and strong aroma.
IV
Origin
It is mainly produced in Guangdong, Guangxi, Fujian, Yunnan and other places.
Woo
Ancient and modern efficacy
The 2020 edition of the Pharmacopoeia of the People's Republic of China records that Jiulixiang is "pungent, slightly bitter, and warm; There is a small poison. Return to the liver and stomach meridians. Qi relieves pain, invigorates blood and dissipates stasis. It is used for stomach pain, rheumatic paralysis pain; External treatment of toothache, swelling and pain, insect and snake bites. ”
Modern chemical component studies have shown that nine-mile is rich in coumarins (such as nine-mile carrycin, nine-mile hydrone, nine-mile propanthin, new nine-mile line, non-nine-mile aldehyde, osthole, anhydrophyllum longifolia, hesperidolactone, umbelliferine lactone, scopolamine), flavonoids (such as sweet orange flavonoids, isoorange flavones), alkaloids (thymetic lidine D, thymetic lidine E, thymetic lidine F, as well as yuetangine, indole-3-carboxaldehyde, thymetic lidine A, thymetic lidine B, thymetic lidine c) and other ingredients. Traditional Chinese medicine Jiuli flavor pungent, with aromatic flavor, volatile oil is also one of its active ingredients, mainly sesquiterpene and monoterpene, such as bicyclolic caryophyllene, -caryophyllene, -caryophyllene, spoon leaf eucalyptol, etc.
Modern pharmacological studies have shown that the compounds in Thyme have significant anti-inflammatory effects. For example, flavonoids extracted from Nine-mile can inhibit LPS-induced mouse macrophages and RAW2647. The production of nitric oxide (NO) and interleukin IL-6 in a dose-dependent manner in a model of cell inflammation; The study on the anti-inflammatory and analgesic activity of the 70% ethanol extract of the leaf showed that the 70% ethanol extract of the Lycaum sinensis significantly reduced the twisting reaction induced by acetic acid and increased the latency of the hot plate reaction in mice, indicating that the 70% ethanol extract of the Lycopodium chinensis had centrally-mediated and peripheral-mediated analgesic effects, and could effectively reduce the ear swelling caused by xylene and the foot swelling of rats caused by carrageenan. Thyme leaf 50% ethanol extract has a good hypoglycemic effect on alloxan-induced diabetic rats, and can reduce blood glucose, cholesterol and triacylglycerol levels in diabetic rats after 1 week of using thyme extract**. The blood glucose values of rats tended to be normal, and the values of fructosamine and glycosylated hemoglobin decreased. In addition, 50% ethanol extract of thyme leaf can also reduce the morphological changes of the kidneys, pancreas and liver caused by diabetes.
Land
Product Applications
It has only begun to enter the clinical practice of traditional Chinese medicine in modern times, so it is less widely used in ancient prescriptions and modern Chinese patent medicines.