In vitro fertilization, hormone six items are routine items of female reproductive system examination, and through the measurement of sex hormone levels, you can understand your own endocrine function and diagnose diseases related to endocrine disorders. Therefore, usually before the test tube, women need to undergo hormone six tests, yin ultrasound and AMH in the hospital, so as to provide a basis for the test-tube doctor to understand the actual physical condition of the woman in detail.
Note: There are six hormones, including follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone (P), testosterone (T), and prolactin (PRL).
So, if the female luteinizing hormone (LH) is high, does it have an effect on the implantation of IVF embryos? How can IVF doctors help improve blastocyst implantation rates?
What is luteinizing hormone (LH)?What are the effects on fertility?
A glycoprotein-like gonadotropin secreted by basophils in the anterior pituitary gland of the LH that promotes the conversion of cholesterol into sex hormones in gonadal cells. For women, LH works together with follicle-stimulating hormone (FSH) to promote ovulation and estrogen secretion of the ovaries, maintain the menstrual cycle of the ovaries, form the corpus luteum and secrete progesterone.
During a woman's menstrual cycle, the peak release of LH is closely related to ovulation of the ovaries. In the pre-ovulation period, the LH is 2 15 miu ml, the ovulation period is 30 100 miu ml, and the late ovulation period is 4 10 miu ml, and the peak of LH indicates ovulation in the ovaries in 24 to 36 hours.
When performing the six hormone tests, the base LH value in the range of 5-101u L is ideal. If it is higher than the normal range, it may be ovarian dysplasia, premature ovarian failure, etc.; Too low may be due to pituitary gland dysfunction. In addition, if the LH is high and the FSH value is also high, then it indicates ovarian failure; LH FSH 3, which can be diagnosed as polycystic ovary syndrome.
Analysis: Effect of luteinizing hormone (LH) on embryo implantation.
If a woman's LH value is too low or too high, it will directly affect ovarian function and lead to ovulation disorders. In addition, the level of LH blood concentration can promote or inhibit the release of estrogen and progesterone hormones, which has a significant effect on the metabolism of endometrium and smooth muscle, promotes the growth of endometrium, and makes it reach a thickness suitable for embryo implantation. Therefore, if the LH value is abnormal, it will lead to insufficient or excessive secretion of estrogen or progesterone, resulting in too thin or too thick endometrium, which will reduce the receptivity of the uterus, affect the implantation of the embryo, and even lead to pregnancy failure.
The high LH value is an effective strategy to improve the implantation rate of blastocysts in IVF.
If a woman's LH value is too high, it may affect the success rate of IVF. To improve the blastocyst implantation rate, here are some effective strategies:
1. Adjust living habits: It is recommended that women should pay attention to diet, adjust their living and eating habits, achieve a healthy diet, a reasonable diet, maintain a balanced and nutritious intake, and eat more fruits and vegetables. In addition, it is necessary to stop smoking and drinking, maintain adequate sleep, and stay away from radiation; Strengthen physical exercise, such as aerobic exercise, running, swimming, yoga, etc. At the same time, it is necessary to adjust the mentality, maintain a happy mood, and maintain a peaceful state of mind, which will help to improve the success rate of the test tube.
2. Drugs**: IVF doctors will combine women's LH levels, that is, other hormones, to rationally use drugs for conditioning, such as the use of progestogens, gonadotropin-releasing hormone (GNRH) agonists, etc. These drugs can regulate endocrine levels and help restore LH to normal values.
3. Adjust the ovulation induction plan: If the LH level is too high, the doctor may adjust the ovulation induction plan to reduce the LH level. For example, reducing the dose of ovulation induction medication or adjusting the timing of the medication.
4. Improve the quality of the endometrium: The IVF doctor will perform ultrasound and other examinations on women to check the thickness of the endometrium, and learn more about the receptivity of the endometrium and the level of various hormones. By improving the quality of the endometrium, the embryo implantation rate can be increased. Your doctor may recommend measures such as growth hormone, estrogen supplementation, etc., to promote the growth and development of the endometrium.
5. Seek the help of an IVF doctor: The IVF doctor will conduct ultrasound and other examinations on women to check the thickness of the endometrium and learn more about the receptivity of the endometrium and various hormone levels. If the female endometrium is too thick to achieve the ideal transfer state, the uterus is poor receptivity, and the LH level is abnormal, then the doctor will first condition, and then implant the blastocyst after returning to normal, which will help the embryo implant smoothly and grow and develop until full-term delivery.
In addition, after implantation, the IVF doctor will also use an appropriate amount of natural drugs according to the actual situation of the woman to regulate the levels of various hormones in the woman's body, help improve the receptivity of the uterus, and make the blastocyst implant better. At the same time, we also advocate expectant mothers to take tocolytic drugs (such as ** suppositories and belly patch drugs, etc.) until 10 weeks of pregnancy, and advocate to eat some health products (such as folic acid, vitamins, deep-sea fish oil (DHA), etc.) within 10 months of pregnancy, so as to provide favorable conditions for the growth and development of the fetus. Maintain your pregnancy and ensure a smooth and successful pregnancy.