Family gatherings, friends dinners, company team building, work socializing, ......All kinds of hospitality and hard to resist wine parties followed.
The most unbearable thing is that every time there will be a few guys who drink particularly "rolled", so that you, who want to "drink", have to "blow the whole bottle" and "step on the box to drink".
However, only I understand the pain of headaches, fragments, and ** when I drink them.
If you have to consider the sophistication of people and the efficiency of your work, and on the other hand, you have to worry about your health, then you have to understand these things!
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part 1
Pay attention to these 3 points, and you may be able to reduce some damage
It's inevitable that you're going to sit at the wine tableThen pay attention to these things and try to reduce the damage as much as possible.
1. Avoid drinking alcohol on an empty stomach
Drink some milk, yogurt, or eat foods high in protein and carbohydrates, such as beef, eggs, millet porridge, steamed buns, bread, etc., to increase fullness and reduce the irritation of alcohol on the gastric mucosa.
After all, before the table even started, there were often guys who raised their glasses and raised a glass first. With an empty stomach and no food to resist, alcohol penetrates more quickly and is more likely to get drunk [1,2]. In addition, drinking alcohol in a fasting state may lead to depletion of stored hepatic glycogen and decreased glucose production, leading to alcoholic hypoglycemia [3].
2. Avoid drinking with carbonated drinks
Drinking liquor is too strong, let's mix it with some beer or Coke to relieve it, and I haven't successfully stolen the fun because of "escaping from alcohol", why does it seem to be more dizzy?
This is because beer, champagne and various carbonated beverages contain carbon dioxide, a gas that inflates the stomach like a balloon and squeezes alcohol out of the stomach and into the small intestine, where it is more easily absorbed [4].
So when you go to the bar, be sure to order carbonated cocktails, such as Long Island Iced Tea, the main ingredient is a cola mixed spirit, which tastes like black tea, and tastes sweet and sour, but you may be unconscious after a glass.
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3. Try eating some of the following foods
The discomfort of being drunk is comparable to that of a person who is afraid of heights after playing a roller coaster, so there is always some way to "relieve hangover".
Although scientifically speaking, there is no definitive hangover cure, there are natural foods that can be eaten to help relieve discomfort [5,6], such as:
Honey: Contains special fructose to effectively decompose and absorb alcohol, and can reduce headache and dizziness after drinking
Fruits and vegetables (juice) such as limes, pears, and tomatoes: It can enhance the activity of ethanol dehydrogenase and aldehyde dehydrogenase, and increase the rate of ethanol metabolism[7];
Yogurt: Fermentation of milk can turn lactic acid into fine curd grains, delaying alcohol absorption [8].
In addition, alcohol depletes large amounts of vitamin B1 in the body, resulting in vitamin B1 deficiency [9]. People who can't avoid drinking can supplement more foods rich in vitamin B1, such as animal liver, peanuts, soybeans, etc.
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part 2
Don't be bored if you have deep feelings
If you want to get closer to the relationship and negotiate cooperation at the wine table, the wine must be drunk in place. "Feelings are deep and stuffy", the wine is drunk in place, but it may cause acute ethanol poisoning.
The clinical symptoms of ethanol poisoning are mainly divided into three periods (you can see how much you usually drink) [2]:
Excitement - redness, chattering - drinking;
The period of ataxia—staggering, incoherent—has drunk gaffes;
Sleepy — pale, pulse-quick, unconscious — drank fragments.
See! Strictly speaking, it's not about drinking until you get hospitalized is alcoholism, and it's time to take it away when you drink until you blush and talk a lot!
Not only that, but the long-held belief that "drinking in moderation is good for your health" is also wrong.
Recent studies have shown that there is no safety line for drinking, and that the safest amount of alcohol to drink is 0 [10].
If it's really hard to quit drinking, keep the amount of alcohol you drink to a moderate level.
The Chinese Nutrition Society recommends in the "Dietary Guidelines for Chinese Residents (2022)".
Adults should consume no more than 15 grams of pure alcohol a day, which is equivalent to 450 milliliters of beer (nearly a bottle), 150 milliliters of wine (the amount of most half a carton of milk) or 50 grams of 38-degree liquor (about the weight of an ordinary egg).
But if you are one of the following groups, it is still recommended that your alcohol intake is 0.
1. People who drink alcohol and blush
There are few hangover enzymes in the body, and alcohol metabolism is slow. As soon as you drink alcohol, your face is red, and to put it bluntly, it is ethanol poisoning.
2. Patients with chronic diseases
Those who have heart disease, diabetes, liver disease, cerebrovascular disease, gastric disease, high blood pressure, and hyperlipidemia.
3. Pregnant women, nursing mothers, adolescents and children
part 3
For some people, the amount of alcohol can only "moisten the lips".
Sometimes you will hear the words "drink a few more times" and "the amount of alcohol is practiced slowly" at the wine table, but don't believe it!
The amount of alcohol is actually the body's ability to metabolize alcohol, and the level of metabolism mainly depends on the two hangover enzymes in the body: alcohol dehydrogenase and aldehyde dehydrogenase.
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Alcohol is like a puzzle that needs to be filled in the blanks, but the shape is not in the same way.
Ethanol dehydrogenase pruned it first to make it become "acetaldehyde", but it was still a little wrong, so acetaldehyde dehydrogenase repaired it again, so that it finally became "acetic acid". However, after the conversion to acetic acid, the "harmless treatment" of alcohol is completely completed [11,12].
The intermediate product "acetaldehyde" will be metabolized by the liver, causing damage to liver function, and even causing alcoholic liver, fatty liver, liver cirrhosis, liver cancer and other diseases.
Those who blush after drinking a little alcohol basically lack "hangover enzymes" in their bodies. The "hangover enzyme" is mainly determined by genes, and it cannot be changed by more exercise in the later stage.
The more I drank alcohol, the less uncomfortable my body felt, as if I had developed the skill of "not getting drunk after a thousand drinks", just because the body's sensitivity to alcohol had decreased. Acetaldehyde, which cannot be decomposed, will still accumulate in our body and damage our health.
The wine table is not a battlefield, so don't be reckless.
People who are easy to get on the face of drinking should try not to drink at all. The amount of alcohol is okay, but you should also pay attention to the amount and manner of drinking.
After all, health comes first.
end - Audit Specialist. 
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9] Hu Peng, Zhan Ke, Zhang Li, Luo Wen, Gao Yuan Ju. Research on natural hangover drugs and foods[J].Journal of Changchun University of Traditional Chinese Medicine,2011,27(01):137-138
10] gbd 2016 alcohol collaborators. alcohol use and burden for 195 countries and territories，1990 -2016：a systematic analysis for the global burden of disease study 2016［j］.lancet，2018，392（10152）：1015-1035.
11] Yang Yinping. Codon optimization and molecular cloning of human acetaldehyde dehydrogenase 2[D].Zhejiang Gongshang University, 2018
12] Scientists at Fudan University discovered that East Asians have a unique "hangover gene" [J].Fudan Journal (Natural Science Edition),2011,50(04):510