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Folic acid, a B vitamin, is essential for human health. It is involved in the synthesis and repair of DNA, and has special significance for pregnant women and fetal development. However, studies in recent years have shown that excessive folic acid supplementation may be associated with an increased risk of liver cancer. This article will discuss the effects of folic acid, the risk of overdose, and who should supplement with folic acid and the principle of moderation.
The role and importance of folic acid.
Folic acid, also known as vitamin B9, is a water-soluble vitamin. In the human body, folic acid is involved in cell** and growth processes, especially playing a key role in DNA synthesis and repair. Folic acid supplementation in pregnant women can significantly reduce the risk of neural tube defects in the fetus, such as spina bifida and anencephaly. In addition, folic acid has a positive effect on erythropoiesis, immune function, and cardiovascular disease risk.
Risk of excess folic acid.
Although folic acid is essential for human health, excessive intake may lead to adverse effects. One study found that men who had been supplementing too much folic acid for a long time had a higher risk of liver cancer. The mechanism may be related to the promotion of cell growth and ** by folic acid, which may increase the risk of cancerous cells. However, more research is needed to confirm this finding.
Who needs folic acid supplementation.
Not everyone needs additional folic acid supplementation. In general, people who eat a balanced diet can get enough folic acid through food. However, some specific groups of people may require additional folic acid supplementation:
1.Pregnant women and women planning pregnancy: To reduce the risk of fetal neural tube defects, additional folic acid supplementation is recommended for pregnant women and women planning to become pregnant.
2.Older people: As we age, folate absorption and utilization may decrease, so older people may need additional folic acid supplementation.
3.People with certain medical conditions, such as Crohn's disease, malabsorption syndrome, etc., which may affect the absorption and utilization of folic acid and require additional supplementation.
4.People who take certain medications for a long time, such as certain anti-epileptic drugs, gastric acid suppressants, etc., which may affect the absorption of folic acid and need additional supplements.
How to supplement folic acid in moderation.
So, how do you determine the right folic acid intake? Here are some suggestions:
1.Follow professional advice: Talk to your doctor or dietitian about the right folic acid intake for your individual situation before supplementing with folic acid.
2.Food**: Prioritize folic acid intake through food. Green vegetables, legumes, citrus fruits, whole grains, etc. are all good for folate**.
3.Folic acid supplements: If you need additional folic acid supplements, choose a high-quality folic acid supplement. Folic acid supplements are available in many forms, including tablets, capsules, and liquids.
4.Avoid overdose: Follow the recommended dosage and avoid overdose of folic acid. Excessive folic acid may lead to adverse effects such as nausea, stomach pain, etc.
Conclusion. Folic acid is essential for human health, especially for pregnant women, women planning to become pregnant, and certain populations. However, excessive folic acid supplementation may be risky, such as an increased risk of liver cancer. Therefore, it is recommended to supplement folic acid in moderation under the guidance of professionals to ensure that the intake is within a safe range. With a balanced diet and proper supplementation, we can enjoy the health benefits of folic acid while reducing the potential risks.
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