What is the relationship between purine, uric acid, and gout?
1.1 Purine is simply understood as adenine and guanine in DNA base pairs.
1.2 Purines are metabolized in the body to become uric acid. Uric acid can be produced by the metabolism of nucleic acids, amino acids, small molecule compounds.
1.3. If uric acid is high for a long time, it will form a stone-like lens and accumulate around the joint, which will lead to joint pain and gout.
High uric acid is an unhealthy condition that is worth noting, but high uric acid is not the same as gout. Gout is a term used to describe joint pain caused by high uric acid.
Why is uric acid high?
** of uric acid, excretion of uric acid.
Uric acid**: Eaten food and drugs are metabolized into uric acid, which is exogenous and accounts for 20% of the total uric acid in the body; The body metabolizes its own uric acid (metabolism of nucleotides, nucleic acids, amino acids, small molecule compounds), which is endogenous and accounts for 80% of uric acid in the body;
Excretion of uric acid: Uric acid is excreted in the urine. In 90% of patients with primary hyperuricemia and gout, uric acid excretion is reduced and uric acid production is normal.
By understanding the ** and excretion of uric acid, it is not difficult to find that food has less effect on uric acid, accounting for only 20% of uric acid**. Discharge problems account for up to 90%.
How to solve high uric acid? (The following degrees of importance are in descending order).
3.1. Drink plenty of water and urinate more. This is the most important thing.
3.2. If you have obesity problems, you should do fat loss exercises.
3.3. Reduce the generation of competitors. Urine is limited in what it can hold, and so is the amount of urine the body can produce. In the limited solvent, there are more other metabolites, and uric acid is naturally less. Competitors are:
3.2.1 ketone body, a low-carb diet produces ketone bodies. Therefore, there needs to be enough carbohydrates in the diet.
3.2.2 lactic acid, lactic acid is produced by anaerobic exercise. It is not recommended to do strenuous exercise, strength training, if necessary, it can be judged according to the actual situation.
3.4. Reduce the intake of fructose, which can increase the production of uric acid.
3.5. Reduce alcohol intake, which increases lactic acid production.
3.6. Reduce the intake of high-purine foods.
Common misconceptions: If you have high uric acid, the most important thing is to avoid eating and drinking.
In fact, diet is a relatively small influence on the cause of high uric acid. More importantly, focus on increasing uric acid excretion. You can pay a little attention to your diet, such as broth, beer, seafood, animal offal, honey, etc.
High protein High purines.
Actually, eggs and milk are high-protein foods, but they are relatively low in purines. In beans, the beans themselves may be relatively high, but soy products are generally lower than beans, so soy products can still be eaten. A lot of meat can also be eaten, although they are high in purines, but considering that it is not the main way to raise uric acid, they can be eaten.