Mechano growth factor
Mechanogrowth factor (MGF) is a peptide with a different sequence than insulin-like growth factor-1 (IGF-1), which plays an important role in child development and continues to have anabolic effects throughout adulthood. MGF (mechanical growth factor) is released when muscles are stretched and exercised. This is especially abundant when muscles are exposed to high-intensity weight training.
MGF is able to promote the repair and growth of discarded tissues by activating muscle stem cells, thereby increasing the synthesis of proteins required for tissue growth. this peptide is ideal for anyone suffering from muscle loss, either due to old age or a particular condition.
Benefits of MGF:
Activates muscle satellite stem cells.
Triggers the fusion of satellite stem cells with muscle fibers.
Provide satellite cells with the extra nuclei they need for repair.
It is essential for the restoration, repair, and growth of new cells.
How MGF works:
IGF-I is spliced with MGF, and MGF initiates hypertrophy and repair of local muscle injury. MGF is expressed by mechanically overloaded muscles and is involved in tissue repair and adaptation. It is expressed in the form of pulses after muscle injury and is involved in the activation of muscle satellite stem cells. These donate nuclei to the muscle fibers needed for repair and hypertrophy processes. MGF is essential for the repair and growth of new cells, similar to IGF-1. If the MGF is not PEGylated, the half-life is a few minutes, therefore, PEGylated MGF must be considered during the formulation process to ensure an appropriate half-life and thus increase the duration of the action.