An elderly friend left a message saying that he had a chronic disease and had to take antihypertensive drugs, lipid-lowering drugs, and aspirin every day. Every time he took medicine, he got up in the morning and threw all the medicine into his mouth and took it together. He wondered if there was a problem with the way he took the pills and if there was the right time to take them.
In fact, this method of taking medicine is not completely wrong, but it is necessary to analyze it specifically to know whether the method of taking medicine is reasonable.
Let's start with aspirin
Aspirin is an antipyretic analgesic non-steroidal anti-inflammatory drug, antiplatelet aggregation drug, white crystalline or crystalline powder;Odorless or slightly vinegar sour odor, slightly sour taste;It is slowly hydrolyzed in case of moisture, mainly by inhibiting the synthesis of prostaglandins, bradykinins, histamine, etc., to produce antipyretic, analgesic and anti-inflammatory effects.
The antipyretic mechanism of action is to dilate the peripheral blood vessels by acting on the hypothalamic thermoregulation center, increasing blood flow and heat dissipation, and achieving a cooling effect, and its analgesic effect is a peripheral analgesicIt can also inhibit platelet aggregation by inhibiting cyclooxygenase of platelets, reducing the production of prostaglandins, and causing platelet aggregation to occur.
It is widely used as an antipyretic analgesic in clinical practice, and is currently used for the prevention and treatment of cardiovascular and cerebrovascular embolism. It mainly damages the gastrointestinal tract, nervous system, blood system and causes allergic reactions.
When is the best time to take aspirin?
Aspirin is the best effect when eaten on an empty stomach in the morning, and at present, aspirin is an enteric-coated preparation in clinical practice, because aspirin itself has a strong irritation to the stomach, so it is coated with a layer of enteric-coated preparation.
When aspirin enters the gastric juice environment, it prevents it from being disintegrated and absorbed in the stomach and causes damage to the gastric mucosa.
If taken after a meal, the food in the stomach will prevent aspirin from entering the intestines from the stomach and will disintegrate in the stomach prematurely, causing irritation to the stomach. Therefore, aspirin is best taken in the morning on an empty stomach.
What are blood pressure medications?
Antihypertensive drugs are drugs used to lower blood pressure by changing the physiological state of the heart and blood vessels.
In general, antihypertensive drugs can be classified into several types, including diuretics, receptor antagonists, calcium channel blockers, angiotensin-converting enzyme inhibitors (ACE inhibitors), and angiotensin receptor antagonists. These drugs have different mechanisms of action, but they all lower blood pressure by reducing the burden on the heart and dilating blood vessels.
Before using blood pressure medications, you should consult your doctor about your blood pressure status and the mechanism of action of blood pressure medications. Your doctor will prescribe a suitable antihypertensive medication** regimen for you based on your specific situation.
When is the best time to take blood pressure medication?
Generally speaking, our blood pressure levels fluctuate regularly every day: there are two peak blood pressure times in 24 hours, that is, 6 to 10 a.m. and 4 to 8 p.m. (the so-called "spoon curve"), then taking the medicine half an hour before these two peaks will have a better antihypertensive effect.
However, there are some special circumstances, such as some patients whose blood pressure rises in the early morning, then they need to take the medicine once before bedtime.
But then again, most people fall asleep at night when their blood pressure drops by about 20% compared with the day, so taking antihypertensive drugs before going to bed can easily lead to a large drop in blood pressure, resulting in insufficient blood supply to organs such as the heart, brain, and kidneys, so whether to take medication before going to bed must consult your doctor on the basis of blood pressure monitoring.
Statins are lipid-lowering drugs, which are mainly used for cardiovascular diseases with high blood lipids, such as hyperlipidemia, hypertension, atherosclerotic heart disease, etc.
Statins
At present, the commonly used statins in China include simvastatin, lovastatin, fluvastatin, atorvastatin, pravastatin, rivastatin and its pitavastatin.
It can also be used for non-lipid regulation, improve the function of intravascular cells, inhibit the proliferation of vascular smooth muscle cells, antioxidant, anti-inflammatory, inhibit platelet aggregation and antithrombosis, and help prevent the formation of arteriosclerosis.
When is the best time to take statins?
This type of drug is generally taken after meals or before going to bed, so patients may have a better effect during these two time periods, because the drug is more irritating to the gastrointestinal tract, taking it after meals can reduce the damage to the gastrointestinal tract.
In addition, taking it before going to bed is because the cholesterol in the blood is mainly synthesized and released at night when sleeping, and the effect of statin drugs is to inhibit the synthesis of cholesterol, so taking drugs before going to bed can maximize the lipid-lowering effect of such drugs.
Doctor reminds:
Master the time of medication, the effect of the drug can be doubled, but no matter when the drug is used, the patient should be under the guidance of the doctor, and pay attention to not adjust the dosage of the drug by themselves, after the drug should be checked regularly to check the cholesterol in the blood, clear the best effect of the drug, can be convenient to adjust the drug method in time.