As the flu season begins, the number of flu patients has increased dramatically, and the demand for flu-specific drugs has also increased. Among them, mabaloxavir has obviously become an "Internet celebrity" influenza drug that has attracted much attention due to its ease of use and efficacy. However, the use of mabaloxavir is not suitable for all patients and certain precautions need to be followed. In addition, recently, the ** of mabaloxavir in the market has also appeared by a large margin, which has aroused people's attention. This article will provide a detailed description of the appropriate patients for mabaloxavir, precautions for use, and the most important questions of the drug.
As a new type of anti-influenza drug, mabaloxavir has certain limitations on its application to the patient population. According to the recommendations of the relevant medical institutions, mabaloxavir is indicated for the following populations:
1. ** and children aged 5 years and above with uncomplicated influenza A and B;
2.Influenza patients at high risk of influenza-related complications** and children 12 years of age and older.
It is important to note that mabaloxavir is not suitable for common cold patients. Therefore, it is necessary to ask a doctor to give an exact diagnosis before use, and to use the medicine rationally under the guidance of a physician and pharmacist.
If you want to use mabaloxavir, care must be taken to avoid interactions with other medications. According to the research article of the Second Affiliated Hospital of Xi'an Jiaotong University, mabaloxavir should be avoided with dairy products, calcium-fortified drinks, and **cationsLaxatives, nonantacids, and oral supplements containing calcium, iron, magnesium, selenium, aluminum, or zinc are taken at the same time, as these substances may affect the absorption of the drug and thus the efficacy. If you have to take these preparations, it is best to take them more than 1 hour apart from mabaloxavir.
In addition, for:Pregnancyfemale, due to mabaloxavir toFetusThe impact has not yet been clarified, so inPregnancyshould be avoided;Breastfeeding women should stop breastfeeding or avoid taking mabaloxavir while taking it to avoid harm to the baby through the milk. For renal impairment orLiver functionFor patients with severe damage, there is a lack of research data and the use of mabaloxavir is not recommended.
Mabaloxavir is a novel anti-influenza virus drug that, unlike traditional anti-influenza drugs, is an RNA polymerase inhibitor that effectively inhibits the replication of influenza viruses. Compared with other anti-influenza drugs, mabaloxavir has the following advantages:
1.Easy to use: Due to the long half-life of mabaloxavir, it only needs to be taken at one time, saving the trouble of taking multiple doses.
2.Efficacy: Studies have shown that early use of mabaloxavir can effectively shorten the course of influenza and reduce symptoms, helping patients to do it faster**.
1.Time window: For best results, mabaloxavir should be started within 48 hours of the onset of flu symptoms, the sooner the better.
2.Individualized dose: The dose is calculated according to body weight, children weighing less than 20 kg are calculated as 2 mg kg, ** and children weighing between 20 and 80 kg are given 40 mg at one time, and ** and children weighing more than 80 kg are given 80 mg at one time.
3.Before or after meals: The use of mabaloxavir can be done before or after meals, not withoutDietimpact.
Vaccination: Important, anti-influenza drugs are not a substituteInfluenza vaccine, vaccinated annuallyInfluenza vaccineStill the best way to prevent the flu. In addition, patients who have used mabaloxavir within 17 days prior to vaccination are contraindicated from vaccinationLive attenuated vaccinesso as not to affect the efficacy of the vaccine.
Recently, on the online drug purchase platform, the ** of mabaloxavir has appeared obviously**, which has aroused people's attention. According to the investigation of Red Star News, the price of many pharmacies reached 418 yuan per box, and the price of a single tablet** exceeded 200 yuan. And in public hospitalsMedicinesIn the announcement, the price of a box of mabaloxavir is 22236 yuan. The main reasons are as follows:
1.Market demand has increased dramatically: After entering the flu season, the number of flu patients has increased sharply, and people's demand for influenza drugs has also increased, which has led to an imbalance between supply and demand, and drug prices have become an inevitable result.
2.High cost of imported drugs: As an imported drug, the cost of mabaloxavir from R&D to production is relatively high, which is also an important reason.
3.Market shortage: At present, mabaloxavir, as a new drug, is not sufficient in the market, which also leads to the price of the drug being raised to a certain extent.
It is important to note that mabaloxavir has been included in the national health insuranceMedicinescatalog, so patients can pay a portion of the cost through Medicare. At the same time, ** is also actively taking measures to regulate drug prices to ensure the drug needs of patients.
While mabaloxavir has become a high-profile drug for flu season, we should not neglect to prevent it. In terms of influenza prevention and control, the following points deserve our attention:
1.VaccinationInfluenza vaccine, vaccinated annuallyInfluenza vaccineStill the best means of preventing influenza, especially for susceptible and high-risk groups, vaccination can greatly reduce the risk of infection.
2.Pay attention to personal hygiene Xi: Washing hands frequently, avoiding contact with flu patients, avoiding touching the face, eyes, mouth, etc. can reduce the chance of virus transmission.
HealthDiet: BalancedDietEat moreFruitswithVegetablesGetting enough sleep and exercising is OKBoosts immunityto reduce the likelihood of infection.
4.useMasks: Wear in crowded places and when in contact with people with influenzaMasksThe risk of virus transmission can be reduced.
In summary, mabaloxavir, as a new anti-influenza drug, has a large increase in demand during the influenza season. However, there are restrictions on the use of mabaloxavir for patients who need to follow the guidance of physicians and pharmacists. In addition, flu prevention is still the best option, and getting vaccinated every year and paying attention to personal hygiene Xi can reduce the risk of infection.