Breast cancer is one of the leading killers of women, with high morbidity and mortality. Diagnosis and ** of breast cancer require precise molecular typing, and molecular information about breast cancer can be obtained through needle biopsy. This article will discuss the importance of breast cancer puncture and the significance of molecular typing.
1. The importance of breast cancer puncture
Breast cancer is a disease that emphasizes molecular typing. Whether it is early-stage breast cancer, locally advanced breast cancer, or distant metastatic breast cancer, a needle biopsy is required to obtain molecular information about breast cancer patients. Through puncture, hormone receptor status (including ER, PR), HER-2 status, and metastasis of breast cancer patients can be understood.
If there is no axillary metastasis in the early stage of breast cancer, only a local lump in the breast needs to be punctured. If there are axillary metastases, the axillary puncture is also required. If there is a distant metastasis, it is recommended to puncture the distant transfer organ. Breast cancer is a systemic disease, and a comprehensive understanding of the molecular properties of the tumor is required through puncture.
2. Molecular typing of breast cancer
Breast cancer can be classified based on different molecular markers. Common molecular types of breast cancer include hormone receptor-positive, HER-2-positive, and triple-negative breast cancer. Hormone receptor-positive breast cancer is sensitive to endocrine**, HER-2-positive breast cancer is sensitive to targeting**, and triple-negative breast cancer is sensitive to chemotherapy.
3. Needle biopsy and B-ultrasound guidance.
Needle biopsy is an important means of obtaining molecular information about breast cancer. Through B-ultrasound-guided needle biopsy, the lymph node mass can be roughly identified and analyzed for metastasis. It is important to note that while a local breast mass may be hormone receptor-positive, its molecular typing may be altered at the site of metastasis. For example, when localized in the breast, the tumor may be strongly HER-2 positive, but at the site of liver metastases, it may no longer be hormone receptor positive or HER-2 positive.
4. Application of needle biopsy in breast cancer**.
The development of breast cancer needs to be individualized according to the molecular typing of the patient. The molecular information obtained from needle biopsy of breast cancer can provide clinicians with an important basis for decision-making. For example, patients with hormone receptor-positive breast cancer can undergo endocrine**, patients with HER-2-positive breast cancer can undergo targeting**, and patients with triple-negative breast cancer are better candidates for chemotherapy.
V. Conclusions
Breast Cancer Breast cancer needle biopsy is an important tool for diagnosing and ** breast cancer and can provide clinicians with important information about the molecular typing of breast cancer. Through precise molecular typing, clinicians can develop more personalized and effective protocols to improve the survival and quality of life of breast cancer patients.