Is carbon disulfide toxic?

Mondo Health Updated on 2024-01-31

Carbon disulfide is an important chemical raw material, which is widely used in man-made fibers, cellophane, chemicals, pesticides, rubber, metallurgy, oil refining and other industrial sectors.

At present, the largest use of carbon disulfide in China is to make viscose fiber, commonly known as rayon, accounting for about 64% of the total;Used as a rubber vulcanization accelerator accounts for about 22%;Used for beneficiation agents accounted for 8%;The remaining 5% is used in pesticides, pharmaceuticals, dyes, petroleum industries, and carbon disulfide and its derivatives are also used in solvents and extractants, pre-sulfuration catalysts, chemical reagents, etc.

Carbon disulfide is toxic, it can be mostly ingested from the respiratory tract, and it can also be absorbed. Of the ingested 1 4 is excreted by breathing, a small amount is excreted by urine, and the rest is metabolically converted. The metabolites in the urine are sulfates and the presence of substances that are positive for the iodine azide reaction, which are used as bioindicators of carbon disulfide exposure.

The minimum lethal dose for human inhalation is 4000 ppm (30 minutes). In acute intoxication, initial agitation and headache are followed by loss of consciousness, lethargy, and death. Polyneuritis of the lower extremities occurs with headache, insomnia, loss of libido, and memory loss with long-term exposure at low concentrations, and can occur when disengaged. Long-term exposure (e.g., 10 years) occurs with vascular damage characterized by retinopathy and kidney disease. The United States and Japan set a maximum allowable atmospheric concentration of 10 ppm (30 mg m3).

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