Introduction:
With the progress of science and technology, recombinant proteins have been more and more widely used in the field of biomedicine. As an important cytoskeletal regulator, the trivet-like protein 1 (COTL1) recombinant protein has great research and application value. In this article, we will introduce the basic characteristics and functions of COTL1 recombinant protein and its applications in various fields.
Catalog Number: PA1000-691
1. Basic characteristics of COTL1 recombinant protein.
Coactosin-like protein 1 (COTL1) is a small molecular weight protein composed of 166 amino acids. It is widely found in the cytoplasm of eukaryotic cells and is characterized by being rich in cysteine residues. CoTL1 recombinant protein has good thermal stability and antioxidant properties, and can maintain its activity and stability over a wide range of temperature and pH conditions.
2. Function of COTL1 recombinant protein.
COTL1 recombinant protein plays an important role in the regulation of the cytoskeleton. It binds to F-Actin (actin fiber) and promotes the remodeling and stabilization of the cytoskeleton. In the process of cell motility, cell** and intracellular material transport, CoTL1 recombinant protein participates in cell morphological changes and movement by regulating the remodeling and kinetic processes of the cytoskeleton.
3. Application of COTL1 recombinant protein.
1.Biomedical research: The intracellular modulation of COTL1 recombinant protein makes it an important tool in biomedical research. Scientists use the interaction of COTL1 recombinant protein and other cytoskeleton-related proteins to explore the structure and regulatory mechanism of the cytoskeleton, in order to better understand the occurrence and development of cell functions.
2.Industrial applications: The thermal stability and antioxidant properties of CoTL1 recombinant protein make it a potential application prospect in the industrial field. Researchers can take advantage of its special properties and apply it to the food industry, feed additives, bioenergy and other fields to provide improvements and innovations for related industries.
Conclusion: As a cytoskeletal regulator, trivet-like protein 1 (COTL1) recombinant protein has a wide range of research and application value. Through further research, we can better understand the function and regulatory mechanism of COTL1 recombinant protein.
References: 1 li, b., luo, z., yan, h., zhao, l., wang, z., xie, j. (2019). cotl1 inhibits cell proliferation and cell cycle progression and promotes apoptosis in breast cancer cells. molecular medicine reports, 19(4), 2747-2754.
2. wu, c., liu, l., zhao, q., cui, j., zhang, y., zhang, j. (2018). coactosin-like protein 1 (cotl1) promotes breast cancer cells invasion through interaction with snail. scientific reports, 8(1), 4254.
3. bae, s., park, s. h., kim, j. y., kang, s. w., lee, w. j., kim, y., cho, s. w. (2020). coactosin-like 1 promotes the invasion of colorectal cancer cells through the activation of rhoa signaling pathway. international journal of molecular sciences, 21(1), 241.