Targeted liposomes Targeted drug carrier customization Ethanol injection liposomes encapsulate drugs
Advantages of liposomes.
1.Wide range of drug loading: fat-soluble drugs can be located between the lipid membranes of the bilayer, amphiphilic drugs can be located on phospholipids at the junction between the aqueous phase and the internal membrane, and hydrophilic drugs can be located in the aqueous phase.
2.Routes of administration are diverse: In addition to the most common routes of administration by injection, liposomes are also suitable for oral, ophthalmic, pulmonary inhalation, and transdermal routes.
3.Targeted: Ordinary liposomes are targeted to liver and spleen tissues, and liposomes can be specifically targeted after being modified by monoclonal antibodies and other antibodies.
4.Long-term effect: Long-circulating liposomes can prolong the retention time of the drug in the blood, which is conducive to increasing the efficacy of the drug.
5.Good histocompatibility: With a similar structure to biofilms, liposomes have good cell affinity and histocompatibility, can be adsorbed around target cells for a long time, and can also directly enter cells and release drugs through lysosomal digestion.
6.It can reduce drug toxicity: after the drug is encapsulated by liposomes, the accumulation in the heart and kidney is much lower than that of free drugs, so the drugs that are toxic to the heart and kidney can be prepared into liposomes to reduce drug toxicity.
7.It can improve drug stability: for some drugs that are unstable in a specific environment, they can be protected by the liposomal bilayer, which can improve the stability of some drugs.