Question: Why is it that my aunt doesn't smoke but has lung cancer, but my uncle who doesn't leave his cigarette is fine?
In the past decade, especially in the last five years, the rate of lung cancer in women has been increasing. Aren't all men who smoke to get lung cancer in our old impressions?Women don't smoke or drink, why are the chances of lung cancer getting higher and higher?According to the World Health Organization's (WHO) International Agency for Research on Cancer (IARC) Globocan 2020 China, it is estimated that in 2020, there were 815,563 new cases of lung cancer in China, which will result in about 714,699 deaths.
Lung cancer is a major disease in many countries around the world, especially in countries with high pollution and high smoking rates.
Nearly 65%.Patients with newly diagnosed lung cancer have never smoked or have quit smoking.
Greatabout 12%.of new cases of lung cancer occur in people who have never smoked.
Smoking is a recognized carcinogenic factor. In recent years, the incidence of lung cancer in non-smoking women has attracted more and more attention.
In the Chinese population, the proportion of lung cancer in non-smoking women is gradually approaching that of smoking men. At the 2022 World Conference on Lung Cancer (WCLC), as one of the 19 shortlisted oral presentations in China, the study "Lung Cancer Risk Prediction Nomogram in Chinese Female Non-smokers" published by the cancer prevention and control research team of Henan Cancer Hospital revealed this phenomenon.
Exploring the high-risk factors of non-smoking female lung cancer patients will help to further screen the high-risk groups of lung cancer, and provide an important reference and intervention basis for early screening, early diagnosis and early treatment of lung cancer.
The cancer prevention and control research team of Henan Provincial Cancer Hospital collected data from 151834 non-smoking women who participated in the urban cancer early diagnosis and early treatment program in Henan Province from October 2013 to October 2019, and systematically evaluated their risk factors such as age, history of chronic respiratory diseases, family history of lung cancer in first-degree relatives, menopausal status, and history of benign breast diseases with the risk of lung cancer.
Zhang Shaokai, director of the Disease Control and Prevention Office of Henan Provincial Cancer Hospital, said that the following five risk factors were found to be related to lung cancer in non-smoking women:
Passive smoking
Wang Qiming explained that second-hand smoke is relatively easy to understand, but in life, smoke remains on clothes, room walls, carpets, furniture and even hair and **, and will also form third-hand smoke, which should also attract our attention. These are passive smoking, which is the most widespread and serious indoor air pollution. It can be said that one person smokes, and the whole family suffers.
Previous lung disease
Such as tuberculosis, chronic bronchitis, emphysema, chronic obstructive pulmonary disease (COPD), etc.
Indoor radiation
Harmful gases such as radon, benzene and formaldehyde produced after house renovation are all factors with a high incidence of lung cancer. In addition, long-term exposure to radioactive substances and carcinogens (such as nickel, silver, chromium, cadmium, beryllium, cobalt, asbestos, etc.) is also an important factor in lung cancer.
Exposure to oil fumes
In the process of cooking food, frying and frying always produce oil smoke, which contains a carcinogen called benzopyrene, which can cause damage to the chromosomes of human cells, and long-term inhalation can induce lung tissue cancer. It is recommended that in ordinary cooking, the range hood must be turned on to reduce the inhalation of kitchen fumes.
Family history of lung cancer in first-degree relatives
Studies have shown that the risk of lung cancer is closely related to family history, and people with a family history of lung cancer will have a significantly higher relative risk of developing lung cancer, and the risk increases with the increase of the number of relatives with lung cancer. People who have one or two first-degree relatives (parents, children, siblings of the same parents) who develop lung cancer have a higher relative risk of developing lung cancer than those without a family history.257 times;If 3 or more first-degree relatives have lung cancer, their relative risk rises to 424 times.
Cells in the human body are constantly metabolized day and night, and a small number of abnormal cells are produced every day. In each of us is a powerful, responsive, well-chopped, and coordinated elite defense force - the immune system, which is constantly working, constantly killing these "abnormal cells", fighting the enemy every moment to protect your health. Under normal circumstances, the body's immune system is constantly monitoring and destroying these abnormal cells, which is medically called "immune surveillance function". Therefore, tumor is actually an immune disease, and when the immunity is not enough to resist, the tumor may form. But what many people are concerned about is how to know that their immune system is in the process of preventing cancer
Fortunately, scientists across the globe have solved this problem. Scientists in the direction of our immune police patrol found that tumor cells will be producedTumor-associated antibodiesto remind us. By detecting the seven lung cancer-related antibodies in the blood, we can see which of the seven gates of the "Lung Immunity City" is in emergencyBased on the "abnormal" hint of a positive test for seven lung cancer-related antibodies, some people can prevent the appearance of lung nodules or lung cancer when they have precancerous lesions;Some people can detect lung cancer at an early stage, which can save lives and families.