From inflammation to cancer, it only takes two years
Uncle Zhang is over 60 years old this year, and his usual hobby is smoking and drinking, and after a long time, his body has also gone wrong. Diagnosed with nausea two years agoReflux esophagitis, non-atrophic gastritis,Thinking that it was just gastritis, I didn't feel at ease after taking some medicine.
However, in October of this year, Uncle Zhang's health deteriorated, and it became difficult to eat and swallow. Came to the hospital again and the results of a gastroscopy biopsy showed"Esophageal poorly differentiated squamous cell carcinoma"., this result made Uncle Zhang unacceptable.
When it comes to inflammation, everyone is familiar with it and has been infected to a greater or lesser extent. But how can a small inflammation be so terrible?
1. German study: the harm of inflammation may be accompanied by a lifetime
Moderate inflammation is a normal response of the body, and it has a certain effect on the resistance of the body and the ability to repair tissue cell damage. However, if there is inflammation for a long time, it will put the body in a state of over-defense, which will have adverse effects on healthThis injury can stay with the person for the rest of their livesIt may also induce a series of diseases.
"Cell".A report was published in the journal byGerman Cancer Research Center and other teamsIn the study, the researchers conducted relevant experiments on mice, and the results found that:
1.Inflammatory stimulation can reduce hematopoietic function
After 4 weeks of recovery, the researchers found that the number of mature blood cells in the stimulated mice did not change significantly, but the cloning ability and proliferation potential of hematopoietic stem cells decreased significantly. To know,Hematopoietic stem cells are the origin of hematopoietic cells and immune cells, and when their function declines, they will affect the normal hematopoietic function of the body.
2.Damage is cumulative and irreversible
The researchers also conducted a bone marrow mixed transfusion experiment on mice, and after 1 year of follow-up, it was found that the hematopoietic stem cells of mice in the inflammation-stimulated group were reduced by about 20 times compared with the control groupAnd the more times you are stimulated,The ability to make blood will get worse and worse, and these injuries will gradually accumulate and be irreversible.
3.Inflammation accelerates cellular aging
In addition, the researchers also measured the level of epigenetic modifications in mice, and found that the genetic age of mice in the stimulus group was greater than that of biological age, in other wordsInflammation is a driver of accelerated aging.
Studies have shown that if inflammation is affected in young and middle-aged years, this injury is likely to accompany the person for a lifetime, and even affect the hematopoietic system in old age.
Second, 50% of deaths are related to "inflammation", which should be paid attention to
Nature MedicineStudies have pointed out that diseases associated with chronic inflammation are one of the leading causes of deathIt is currently attributable to 50% of deaths. Studies have also found that chronic inflammation throughout a person's life significantly increases the risk of death.
It can be said that inflammation is the "soil" that induces the occurrence of a variety of diseases, and these types of diseases must be paid more attention.
1.Cardiovascular disease
Over, long-term activation of the inflammatory response can cause the immune system to release large amounts of pro-inflammatory factors that can cause damage to arterial walls, plaque formation, and, without timely intervention, platelet aggregationIncreased blood clots, myocardial infarction, stroke, etcRisk of disease.
2.Obesity or overweight
Fat cells are:Induces inflammationMacrophages, an important part of the immune system, are also present in the important chemicals that occur, and a large amount of fat accumulation can lead to macrophage infiltration, which further exacerbates the body's inflammatory response.
3.Diabetes
The inflammatory response creates a stress mechanism through oxidation, induces endothelial damage to blood vessels and tissues, and causes the body to develop insulin resistanceCauses abnormal fat metabolism, accelerate the progression of diabetes and form a vicious circle.
4.Neurological disorders
If inflammation is not controlled in time, the nervous system can be poisoned and neuronal cells can be damagedIncreased dementiarisk of occurrence.
3. Diet structure affects health, remember "3 less and 4 more".
Chinese Anti-Cancer Association Tumor Nutrition Professional Committee and other associationsJoint releaseExpert Consensus on Anti-inflammatory Diet for Tumor PreventionIt is pointed out that dietary adjustment is one of the most effective means to change the inflammatory state of the body, and some bioactive components in the diet are of great help to improve the inflammatory response.
If you want to make the inflammation in the body subside, you should pay attention to eating less pro-inflammatory foods and more anti-inflammatory foodsYou can start by reducing the 3 types of pro-inflammatory foods.
1.High-sugar foods, delicate carbohydrate foods
White rice, steamed buns, white bread, cakes, biscuits and other foods have a large amount of mirror carbs, which will cause blood sugar to rise rapidly after consumption, and the internal environment of the body with high blood sugar is very beneficial to the development of inflammation.
2.High-fat foods, fried foods
Some studies have found that mice ingesting a large amount of high-fat food will make the stress response in the small intestine and the response to viral infection in the same way, which is easy to induce systemic inflammation.
3.Red meat, processed meat
Journal of the Second Military Medical UniversityA study pointed out that the body produces a large amount of nitroso compounds and ferrous ions in the process of digesting red meat, which can easily cause inflammation in the body and promote cell cancer.
Reduce intake of pro-inflammatory foodsEat more of these 4 types of anti-inflammatory foodsContributes to our health.
1.Fruits and vegetables
Fruits and vegetables are rich in dietary fiber, vitamins, polyphenols, etc., which have good antioxidant effects and are good for reducing inflammatory responses. Especially in autumn and winter, we should pay attention to eating more fruits and vegetables to prevent water deficiency in the body. Wang Kai, the attending physician of the Nutrition Department of Hebei Provincial People's Hospital, reminded that it is recommended to eat more dark and leafy vegetables in autumn and winter, and fruits should choose seasonal pears and apples.
2.Whole grains
Wheat, oats, corn, sorghum, etc. are all whole grains, which are rich in dietary fiber, and can bind to carcinogens and absorb heterocyclic amines after entering the body, which has certain benefits for intestinal health and inflammatory cell level factors.
3.Fish
Salmon, sardines, mackerel, etc., are all good choices, these fish are rich in omega-3 fatty acids, which help improve inflammation.
4.Tea
Tea is rich in tea polyphenols, which have strong antioxidant and anti-inflammatory effects.
The impact of chronic inflammation on us is subtle, although not obvious, but it accumulates little by little, and may eventually cause irreparable damage. In daily life, we need to develop good Xi habits, eat less pro-inflammatory foods, eat more anti-inflammatory foods, and reduce the impact of inflammation on us.
References: 1] "Once you are young or middle-aged, the harm may accompany you for a lifetime".Life Times 2022-08-22
2] "Remember to "anti-inflammatory diet" to prevent diseases, and avoid "pro-inflammatory diet"!Health Times 2022-02-24
3] "The world's 1 6 cancers are caused by inflammation, and we must pay attention to these 6 types of inflammation."The First Affiliated Hospital of Wenzhou Medical University 2023-06-13
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