Corticosteroids may be required in the following situations**
Substitution**: for acute and chronic adrenal insufficiency, cerebral hypopituitarism, etc.
Autoimmune diseases: such as rheumatic fever, rheumatic myocarditis, rheumatic and rheumatoid arthritis, systemic lupus erythematosus, periarteritis nodosum, polymyositis, dermatomyositis scleroderma, myasthenia gravis, autoimmune anemia and nephrotic syndrome.
Severe infection: It is mainly used for the adjuvant of severe infection with toxemia, such as toxic dysentery, severe typhoid fever, toxic pneumonia, tuberculous meningitis, pericardial pleurisy, fulminant meningococcal meningitis, fulminant hepatitis, etc., but it must be combined with sufficient effective antibiotics as the premise to alleviate inflammatory reactions, protect important organs such as heart, brain, kidney, liver, etc., and help patients get through the dangerous period.
Please note that glucocorticoids are generally relatively large and need to be used under the guidance of a doctor. Long-term use of glucocorticoids in high doses may lead to various adverse reactions, such as inducing or aggravating infection, leading to peptic ulcers, delayed wound healing, osteoporosis, muscle wasting, diabetes, glaucoma, etc.