With the widespread clinical application of hydroxychloroquine, some adverse reactions have also begun to appear. Among them, pigmentation caused by hydroxychloroquine is a relatively common problem.
Pigmentation caused by hydroxychloroquine is due to the drug's stimulating effect on melanocytes. Melanocytes are the cells responsible for synthesizing melanin, and when hydroxychloroquine acts on these cells, it prompts melanocytes to overproduce melanin, resulting in hyperpigmentation.
Pigmentation usually occurs weeks to months after hydroxychloroquine**, most commonly on exposed areas such as the face, neck, and hands. The degree and extent of pigmentation varies from individual to individual, with some people experiencing mild pigmentation while others may experience large areas of pigmentation.
Pigmentation caused by hydroxychloroquine, while it may affect the aesthetics of the company, usually does not have serious health effects. However, for some patients, cosmetic problems due to pigmentation can have an impact on quality of life.
How to prevent pigmentation caused by hydroxychloroquine?
1.Avoid using drugs containing hydroxychloroquine, such as aldipine, chloroquine, etc., at the exposed site.
2.While taking hydroxychloroquine, take care to keep it clean, avoid direct sunlight, and use protection such as sunscreen.
3.If hyperpigmentation occurs, topical medications (e.g., hydroquinone cream, vitamin E cream, etc.) or physical (e.g., laser**) can be used to alleviate symptoms.
In conclusion, hydroxychloroquine-induced hyperpigmentation is a relatively common adverse reaction, but it usually does not have serious health effects. For some patients, the degree and extent of pigmentation can be reduced through preventive measures such as avoiding medications containing hydroxychloroquine, keeping **clean, avoiding direct sunlight, etc. If hyperpigmentation occurs, symptoms can be alleviated with topical medications or physical**.