In recent years, with the continuous progress of science and technology, small automatic freeze dryers have been widely used in laboratories and industrial production. This equipment uses advanced lyophilization technology to quickly dry liquid, solid or semi-solid samples while maintaining their original physicochemical properties and biological activity. Among them, the small automatic lyophilizer with its own pre-freezing function is popular, which has the characteristics of cooling first and then heating, and can quickly and efficiently complete the lyophilization of samples.
1. The working principle of the small automatic freeze dryer.
The working principle of the small automatic lyophilizer is mainly through refrigeration and vacuum technology, which directly sublimates the moisture in the sample from the solid state to the gaseous state, so as to obtain a dry sample. The equipment usually consists of a refrigeration system, a vacuum system, and a control system, among others. In a refrigeration system, the cold trap provides a low-temperature environment that allows the moisture in the sample to freeze rapidlyIn a vacuum system, the ambient pressure is reduced by vacuuming, which provides the necessary conditions for the sublimation processIn the control system, the entire lyophilization process is precisely controlled by automatic control technology.
Second, the characteristics of the pre-freezing function.
A small, fully automatic lyophilizer with built-in pre-freezing function can quickly cool the sample to a low temperature during the pre-freezing stage, so that the moisture in the sample is completely frozen. This is important because the water in the sample can only be removed smoothly during the subsequent sublimation process if it is completely frozen. In addition, the pre-freezing process can also reduce the formation of ice crystals in the sample, thus avoiding the destruction of the sample structure and the deformation of the sample.
In the pre-freezing process, small automatic freeze dryers usually use circulating refrigeration to maintain a low temperature environment by continuously circulating the refrigerant. At the same time, in order to ensure that the moisture in the sample can be completely frozen, the cold trap temperature of the device should be low enough and the pre-freezing time should be long enough.
3. The characteristics of cooling first and then heating.
In addition to the built-in pre-freezing function, the small automatic freeze dryer also has the characteristics of cooling first and then heating. After the pre-freezing of the sample, the equipment will first refrigerate the sample to maintain the sample in a low temperature environmentHeat treatment is then applied to sublimate the moisture in the sample from a solid state directly to a gaseous state.
In this process, the speed and temperature of the heating have a crucial impact on how well the sample is dried. If heated too quickly or at too high a temperature, it may result in loss of nutrients or structural damage in the sampleIf the heating is too slow or the temperature is too low, it will lead to a longer lyophilization time or poor drying results. Therefore, the heating system of the equipment should be adjustable so that it can be adjusted appropriately according to different samples and needs.
Fourth, the application range of small automatic freeze dryer.
Small, fully automatic freeze dryers have a wide range of applications in many fields. In the biological field, it can be used to preserve biological samples such as cells, tissues, and microorganisms to maintain their biological activity and physicochemical properties. In the medical field, it can be used to prepare biological products such as vaccines, antibodies, and proteins, as well as to preserve biological samples such as blood and tissues for medical use. In the field of agriculture, it can be used to preserve agricultural biological resources such as plant seeds and microbial strains. In addition, the small automatic lyophilizer can also be used to prepare special samples such as nanomaterials and chemical crystals.
In short, the small automatic lyophilizer with its own pre-freezing function has been widely used in laboratory and industrial production with its unique advantages. It has the characteristics of cooling first and then heating, which can quickly and efficiently complete the lyophilization of samples, and provides important technical support for research and application in many fields. With the continuous progress of technology and the increase of application demand, small automatic freeze dryers will be more widely used and developed.