Recently, the news that "a father and son in Ningbo, Zhejiang Province were diagnosed with the same cancer one after another" has aroused everyone's attention.
On December 18, according to the Qianjiang Evening News, Mr. Zhang (pseudonym), 65, was diagnosed with bowel cancer five years ago and recovered smoothly after surgery. Before being discharged from the hospital, the doctor learned that Mr. Zhang had four sons, none of whom had ever had a gastrointestinal endoscopy, so he advised them to have a check-up as soon as possible. After that, the second son had a colonoscopy and found a huge polyp in the colon, which had become cancerous, but fortunately it was at a very early stageIt didn't take long for his third son, who was only in his early 30s, to also show symptoms, and he rushed to the hospital for treatment, and sure enough, he was also diagnosed with bowel cancer.
Why father and son.
The same type of cancer was detected one after another
The team of Cui Wei, director of the Department of Colorectal Surgery of Li Huili Hospital of Ningbo Medical Center in Zhejiang Province, received three patients from Mr. Zhang's family and brought their condition under control. Based on Mr. Zhang's family history and genetic testing results, Dr. Cui Wei's team finally found the cause of the disease, Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer.
In this mode of inheritance, carrying just one gene mutation may increase the risk of developing the disease. If one of the couples has a mutation, there is a 50% probability that each of the offspring members will carry the mutation. According to Dr. Cui Wei, most patients with Lynch syndrome inherit it from their parents. If Lynch syndrome has been diagnosed, or if a member of the immediate family has colorectal cancer or reproductive system tumors, it is recommended that both the patient and family members have regular screening. ①
Health Times data map.
7 types of cancer. It is easy to gather in the family!
1.Thyroid cancer.
Wu Yijun, director of the Thyroid Diagnosis and Treatment Center of the First Affiliated Hospital of Zhejiang University School of Medicine, said in an article in Health Times in 2019 that thyroid cancer has a familial tendency. Thyroid disease is often "silent", and the early symptoms are not obvious.
Recommendation: People with high-risk family history should be reminded to screen early, including neck physical examination and neck ultrasound. Like long-term improper iodine intake, too much or too little intake;Women are overstressed;People taking hormones and diuretics;Radiological examination or**;Improper diet is a risk factor.
To prevent thyroid cancer, we should maintain a good mood, eat less spicy and stimulating things, try to quit smoking and alcohol, eat less high-fat and high-cholesterol foods, and eat more vegetables and fruits containing vitamin C, which can reduce the occurrence of thyroid nodules. ②
2.Breast cancer.
Feng Yaojun, deputy chief physician of the Breast Center of Hubei Provincial Cancer Hospital, said in an article in the Health Times in 2018 that if a close relative has breast cancer, the risk of developing the disease will increase. The younger the age of the patient, the greater the risk of breast cancer in relatives.
Suggestion: If these abnormal manifestations occur, they must be checked in time, and mammography, breast ultrasound and other examinations must be performed.
Breast masses are the most common sign of breast cancer, and unlike breast hyperplasia masses, they are often single, irregular in shape, hard in texture, poor in range, mostly painless, and not significantly related to the menstrual cycle. In addition, if nipple eczema, discharge, and wrinkles are found, they should also be taken seriously and go to the hospital for further examination. ③
3.Pancreatic cancer.
Yu Xianjun, chief physician of the Department of Pancreatic Surgery at Fudan University Cancer Hospital, said in an article in the Health Times in 2015 that family members of familial pancreatic cancer are high-risk groups for pancreatic cancer, but family members must not be too nervous to overdo and frequent examinations after a relative is diagnosed with pancreatic cancer, as long as they do regular follow-up monitoring.
For families with 2 or more pancreatic cancer patients in the family, they can register at the hospital, and the experts will formulate a reasonable screening measure and time according to the actual situation.
Recommendation: In general, the starting age of screening is around 50 years old, but for family members with pancreatic cancer less than 50 years old, it should be lower than the youngest age of pancreatic cancer onset 10 years. Screening methods include ultrasound gastroscopy, thin-slice spiral CT, MRI, tumor markers, etc.
Monitoring high-risk groups of pancreatic cancer through regular physical examinations can detect pancreatic cancer or precancerous lesions earlier, and appropriate interventions can be taken in a timely manner.
4.Ovarian cancer.
Wu Xiaohua, chief physician of the oncology ** of Fudan University Cancer Hospital, introduced in an article in Health Times in 2020 that the main feature of a type of ovarian cancer is the occurrence of familial clusters, and the "real culprit" of hereditary ovarian cancer syndrome is the BRCA1 2 gene mutation.
Recommendation: Studies have shown that more than 90% of hereditary ovarian cancers are caused by mutations in the BRCA1 2 gene. For women with a family history of ovarian or breast cancer, it is recommended that people with BRCA1 2 mutations confirmed by genetic testing or effective genetic counseling can undergo prophylactic resection after evaluation by a medical professional to avoid the risk of ovarian or breast cancer. ⑤
5.Hepatocarcinoma.
Wang Qian, deputy chief physician of the Department of Hepatobiliary and Pancreatic Surgery of Henan Provincial Cancer Hospital, introduced in an article in Health Times in 2020 that if parents are diagnosed with liver cancer, children are the target of primary prevention, because the vertical transmission of hepatitis B virus is easy to cause familial aggregation of liver cancer.
Suggestion: If there are hepatitis patients in the family, it is necessary to get vaccinated regularly, and it is recommended to use a separate meal system to avoid cross-use of utensils at home to reduce the spread of hepatitis. If there is a liver cancer patient in the family, their children should have a comprehensive liver examination regardless of whether they are in good health, such as liver function tests, B-ultrasound, etc. ⑤
6.Bowel cancer.
Deng Wenying, chief physician of the Department of Medical Oncology of Henan Provincial Cancer Hospital, introduced in an article in the Health Times in 2020 that if the elderly in the family suffer from bowel cancer, it does not mean that the child will definitely get cancer, but in the same living environment, it is more likely to develop cancer than other groups of people.
Suggestion: If there is a colorectal cancer patient in the family, the immediate family should pay attention to whether there is any change in bowel habits and bowel habits, whether there are constipation, increased stool frequency, pus and blood in the stool, abdominal pain, abdominal distension or intestinal obstruction. If the above symptoms appear, you should go to the hospital for fecal occult blood test, ** digital examination and colonoscopy. ⑤
7.Nasopharyngeal cancer.
Deng Qinghua, chief physician of the Department of Radiation Oncology of the First People's Hospital of Hangzhou, Zhejiang Province, introduced in an article in Health Times in 2020 that several people in a family suffer from nasopharyngeal cancer at the same time. Studies have found that people with a family history of nasopharyngeal cancer are dozens of times more likely to develop the disease than normal people.
Suggestion: If someone in the family has ever had nasopharyngeal cancer, it is recommended that you go to the hospital for a nasal endoscopy and EBV test. ⑤
This article is synthesized from:
2023-12-18Qianjiang Evening News "Father and son were diagnosed with the same cancer, and the culprit was found".
2019-11-19Health Times "Thyroid cancer has a familial tendency".
2018-10-09Health Times "Breast Cancer Family Tendency is Obvious".
2015-09-21Health Times "Familial Pancreatic Cancer Regular Monitoring".
2020-12-22Health Times "Those Family Cluster Cancers".
*: Health Times.