Top news reporter Yang Xiaoyan.
Zhang Teng, who was afraid of injections when he was a child, never thought that he would learn to inject 0 in his stomach by himself because Xi of **25 ml of semaglutide injection.
A lung examination a few months ago made Zhang Teng regain his determination, and some people around him successfully lost weight with semaglutide, and the blog posts such as "prescription drugs" and "* fast" called it "** needle".
Semaglutide injection.
In a month, Zhang Teng lost 25 pounds, and he didn't feel relieved when he saw that the numbers on the scale were updated every day. Stomach pain before falling asleep, tossing and turning in the bathroom and bedroom in the early morning, ** made Zhang Teng's sleep quality take a sharp turn, and he swayed on the balance of whether to continue the injection.
Lost 25 pounds behind it
When deciding to use semaglutide injection, Zhang Teng almost ignored it.
In November 2023, Zhang Teng went to a public tertiary hospital in Zhengzhou according to the process of planting grass and blogging, hung up in the endocrinology department, and the doctor prescribed semaglutide injection for him with clinical diagnoses such as simple obesity and hypercholesterolemia.
Semaglutide prescription order.
But only if I sign a waiver of liability, which is roughly aware of the possible reactions to the medication. Without hesitation, Zhang Teng signed his name and paid more than 800 yuan, and he got the first "** needle".
Zhang Teng is afraid of injections, although the grass text calls ** injection "**injection, which can be operated at home and out", he still chooses to let ** demonstrate his injection, "The needle is very short, and the injection took about 10 seconds, and it really doesn't hurt." ”
When he walked out of the hospital, Zhang Teng imagined that he might be able to return to his target weight this year. He has been fatter than his peers since he was a child, and he has tried a variety of ** methods over the years, such as personal training fitness, ** medicine, 8-hour diet, etc., all popular ** methods, he is happy to try.
It's not that he hasn't succeeded, in the summer of 2017, Zhang Teng went to the gym 5 times a week, high-intensity exercise and extremely harsh diet control, and he did get 30 pounds in 4 months. But after three years of the epidemic, the pressure of work made him inevitably socialize, and regaining weight and ** followed.
Every week in the next week, Zhang Teng went to the hospital to inject a ** injection, and when the dose was insufficient, he needed to increase the dose to 05ml。Following the doctor's advice and exercising, he can see the weight drop every morning, "In a month, I took four injections and lost 25 pounds, basically one pound a day." ”
But is this the least painful way?Zhang Teng said: "There is nothing that is not painful. ”
Painful ***
This is not the first time Zhang Teng has **, but he does feel that this time he has lost weight faster than before.
In June this year, Zhang Teng's new crown "Eryang" turned negative for more than a month, but the dry cough still did not heal, in order to find out**, he went to the hospital to do a lung CT, a small shadow on the lung gland made him sweat.
At that time, the doctor said that it was a malignant tumor and needed follow-up examinations, and my mind was blank at the moment, and I was afraid that I would start the countdown before I was 30 years old. Zhang Teng recalled that he didn't sleep that night.
The in-depth examination lasted for a few days, and the doctor gave the diagnosis that the nodule in the shadow did not need surgery for the time being, and it was first observed by regular physical examination. Despite the false alarm, Zhang Teng re-examined his health state, which was the first "task" he gave himself.
The popular "** needle" is not a new drug in the eyes of doctors - but a GLP-1 (glucagon-like peptide-1) receptor agonist hypoglycemic drug that has been used in China clinically for more than ten years, mainly liraglutide (entered China in 2011) and semaglutide (entered China in 2021), which are used for **type 2 diabetes.
On July 4, 2023, Huadong Medicine's liraglutide injection was officially approved for the treatment of obesity or overweight**. Even more famous than it is semaglutide, and long before it was approved, this weight-loss drug was used off-label on a large scale in ** circles.
There are people around him who have "entered the pit" one after another, and Zhang Teng has also changed from waiting and seeing to deciding to practice. But he obviously underestimated the *** of the needle or the vigorous promotion, and few people mentioned that it was so serious
In order to comply with the doctor's advice, Zhang Teng quit smoking and drinking, and kept exercising, but on the first night of the injection, he couldn't sleep all night. The feeling of nausea made him retch, and the severe discomfort in his stomach in the second half of the night forced him to go to the toilet almost every hour, vomiting and tossing.
Zhang Teng clearly remembers that three days after the first injection, he smelled the smell of vomiting and stomach acid in his mouth, and immediately rushed to the bathroom to retch, and the discomfort of brain congestion and increased heart rate once made him want to give up.
Swinging non-diabetic
After quitting alcohol for nearly a month, a drinking game that couldn't be pushed off made him swing again whether to continue to inject ** injections.
After the injection, I felt that I really didn't feel hungry, and the smell of oil smoke was particularly uncomfortable, so as to control my appetite. This medication inhibits the digestion of food in my stomach, which means that my breakfast may still be in my stomach in the evening. Zhang Teng barely ate at the wine party, and after only drinking a glass of beer, the vomiting sensation from his throat also made him dizzy, so he could only suspend the drinking game.
Wine and food are mixed in the stomach, Zhang Teng burps in the middle of the night are regurgitating stomach acid, "It smells very bad, and I can't control my desire to vomit, my own feeling is that after the injection of ** injection, it is even more uncomfortable if I don't control my diet." ”
Do you want to continue the injection?Zhang Teng flashed this question in his mind every torturous night, and there was a balance in his heart, tilting towards the injection when weighing, but under the severe ***, he swayed to suspend the injection.
However, in the instructions of semaglutide injection, it is detailed that it may cause adverse reactions: including nausea (very common), diarrhea (very common) and vomiting (common).
But after thinking about it, Zhang Teng still chose to buy ** needles. He had already seen the ** injection, and in the second month, he chose to take the drug home and inject it himself. Skillfully unpacking the package, installing the needle, twisting out the liquid, after the injection is completed, he still expects to lose weight a little faster, "Lose weight as soon as possible, I can stop the medicine, and I don't have to be so uncomfortable." ”
Zhang Teng also understands that he is not a type 2 diabetic patient, and the use of semaglutide** is currently non-compliant and risky in China. "Otherwise, I wouldn't have to sign a waiver, but there are countless non-diabetic patients who choose this drug, and since I can buy it, it means that it does have a good effect on weight loss, right?”
The "** needle" in the gray area
It is worth noting that the approval of liraglutide GLP-1 drugs for ** at home and abroad is conditional.
The indication section of the drug states: **Patients with an initial body mass index (BMI) of 30 kg m2 (obese) or 27 kg m2 (overweight) with at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia) should be prescribed by a doctor.
In June 2021, the U.S. Food and Drug Administration (FDA) approved another use of semaglutide: subcutaneous injections once a week24mg for weight loss in obesity.
However, it has not been approved as a ** drug in China. On December 6 this year, Hanyu Pharmaceutical announced that semaglutide injection was approved for clinical trials for type 2 diabetes and does not involve obesity indications.
However, "FDA approval" has become the label of semaglutide as the "best miracle drug". Top news reporters search for semaglutide on the online shopping platform, and need to provide a prescription form, and those without a prescription can issue it online, and they can place an order directly in 2 minutes and wait for the express delivery.
How can people who are not obese get ** injections in the hospital?Zhao Qi, who weighs 110 pounds and is 167 cm tall, shared his buying experience with top news reporters, "Go to a private hospital and tell the doctor that there are some 'enlightened' people who will prescribe obesity, and they can also be used to buy ** injections online." ”
It seems that illegal taking of drugs is an open fact in the weight loss circle. If none of the above methods succeeded, Zhao Qi also recommended buying drug dealers, "Some of them have diabetes prescriptions, you can buy the medicine in their hands at a higher price, about 1,000 yuan or less, or you can buy a prescription and prescribe the medicine yourself." ”
There are relevant reminders for searching for "semaglutide" on social platforms.
Under a number of ** injection blog posts on a social platform, there are many drug dealer advertisements, and some bloggers claim to be harassed by drug dealers in private messages after posting, and they can only remind readers to buy drugs through regular channels in the article and beware of being deceived.
Prescription drugs that are in short supply, abused
In the comment section of online shopping platforms, it is not surprising that drug abuse is occurring.
Hit 0 in the hospital25ml is super unwanted, and the medicine purchased online is 05ml didn't respond at all!"I didn't feel sick to my stomach even after 1ml!One can't lose a few pounds at all. "In addition, the needle needs to be stored in a cool place, and the improper storage method of the drug dealer will also affect the efficacy of the drug, and the loss brought by this time is often borne by the consumer.
Some netizens went to the emergency department for adverse reactions after the injection.
The style of painting is different from the grass text, and it is not uncommon for diabetics to buy semaglutide on social platforms, "all the pharmacies that often prescribe drugs are out of stock, and the family members of diabetes urgently need drugs, and they want to buy them", Awen, a family member of a diabetic patient, said that this phenomenon is very common in 2022, "The ** needle in the eyes of healthy people is actually a life-saving drug for diabetic patients, especially now that semaglutide is included in medical insurance, healthy people, Drug dealers and doctors with no lower limit have taken advantage of the loopholes in medical insurance and diabetics to grab drugs, accelerating their abuse, and patients can only buy them at a higher price. ”
There are also medical aesthetic workers and institutions that package such drugs, under the slogan of "the best needles used by medical care", change their names and surnames and sell them, forming a gray industrial chain.
The top news reporter consulted the customer service of a medical beauty institution, and the answer was that according to the different doses of large and small branches, ** fluctuated between 600 yuan and 1200 yuan, and advertised that "the drug channel comes from the hospital".
Reporter: You can buy "semaglutide" within 2 minutes of prescribing online
In February this year, Xiaohongshu issued a governance announcement saying that it would control the sharing of content that exaggerates the efficacy of drugs such as semaglutide since 2022, and has handled more than 5,000 illegal notes so far. In March, Zhuji City, Zhejiang Province detected a case of semaglutide counterfeit drugs, with a sales amount of more than 100 million yuan, and its "three nos" counterfeit drug products have flowed into more than 20 provinces across the country.
Gao Lingling, secretary general of the Beijing Diabetes Prevention and Control Association, said in an interview that the production of semaglutide is very limited, and the clinical supply exceeds demand, "Novo Nordisk itself cannot supply it, and it is unlikely to sell APIs to other unknown companies."
Under the dazzling ** needle grass blog post, a large number of healthy young people with anxious bodies have emerged. But Zhang Teng said frankly that the ** needle is like Pandora's box, without enough tenacious willpower, with a healthy life and rest, it is difficult to see the benefits.
It seems that to some extent, after he lost 25 pounds by ***, Zhang Teng couldn't help but ask when he saw his acquaintances: "Do you see that I have lost weight recently?"Is it obvious?”
There are differences in personal physique, and the above interview content is for reference only, and the interviewees are pseudonyms).