The arrival of flu season has led to a surge in demand for flu medicines. Recently, mabaloxavir has become a high-profile "Internet celebrity" influenza drug. However, with this comes the price of the drug** and restrictions on who can be used. This article will give a detailed interpretation of the objects and precautions for the use of mabaloxavir, and remind everyone not to blindly believe the so-called "super miracle drug", and the rational use of drugs should be carried out under the guidance of physicians and pharmacists.
Mabaloxavir, as a new anti-influenza virus drug, is very effective for influenza patients. However, not everyone can use mabaloxavir. Based on relevant studies and regulations, the following patient groups are suitable for mabaloxavir:
1.Patients with pre-existing healthy** and children 5 years of age and older with uncomplicated influenza A and B;
2.Influenza patients at high risk of influenza-related complications** and children 12 years of age and older.
This means that the common cold is not suitable for mabaloxavir. Therefore, before choosing to use mabaloxavir, we need to first determine whether we belong to the above applicable groups.
It is important to note that for women during pregnancy, as well as lactating women, it is not clear what the effect of mabaloxavir does on the fetus and whether the drug causes harm to the baby through breast milk, so it is recommended to avoid the drug. In addition, mabaloxavir is not recommended in patients with severe renal impairment and severe hepatic impairment because of the lack of data to determine its safety and efficacy.
1.Time of use: Medical experts state that if you want to use mabaloxavir, it is best to take it within 48 hours of the onset of flu symptoms, and the sooner the better. Therefore, after discovering that you have flu symptoms, you should seek medical attention as soon as possible and consult your doctor to determine whether mabaloxavir is suitable for use.
2.Dosage used: The dose of mabaloxavir is determined based on the patient's weight. The specific calculation method is as follows: children weighing less than 20 kg are calculated as 2 mg kg;For children weighing 20 kg and 80 kg **, a dose of 40 mg is given at a time;For children weighing 80 kg or more, the dose is 80 mg.
3.Time of use: Mabaloxavir can be used for an unrestricted period of time and can be taken either before or after meals.
4.Drug interactions: According to an article from the Second Affiliated Hospital of Xi'an Jiaotong University, mabaloxavir may affect drug absorption and reduce efficacy when used with some dairy products, partially cationic laxatives, antacids, and oral supplements containing calcium, iron, magnesium, selenium, aluminum, or zinc. Therefore, while using mabaloxavir, try to avoid simultaneous use with these drugs and foods and keep an interval of more than 1 hour.
Recently, some patients have reported on social platforms that mabaloxavir is expensive, with a box selling for more than 200 yuan or even more than 400 yuan. We did some research on this issue.
According to a report by Red Star News, the drug announcements of several public hospitals** show that the price of a box of mabaloxavir tablets (specification: 20mg*2 tablets) is 22236 yuan. However, on online drug purchase platforms, the price of mabaloxavir** is generally higher than the list price of hospitals. The price of some pharmacies even reached 418 yuan for boxes, exceeding the price of hospitals by more than 87%, and the price of a single tablet exceeded 200 yuan.
Since mabaloxavir is an imported drug and has been included in the National Reimbursement Drug List, the marketing authorization holder is Roche Pharmaceutical. According to 2021 data, mabaloxavir (trade name: Sufuda) has been approved for marketing in China and expanded its scope of application on March 21, 2023, and can be used in **pre-healthy** and children aged 5 years and older with uncomplicated influenza A and B, or ** and children with influenza 12 years and older who are at high risk of influenza-related complications.
With the arrival of flu season, mabaloxavir has become a special drug for influenza that has attracted much attention. However, we need to be clear about who and what to expect from mabaloxavir. Mabaloxavir is indicated for pre-healthy** and pediatric influenza patients, and is dosed according to body weight and started within 48 hours of symptom onset. At the same time, it is necessary to pay attention to drug interactions and time intervals with eating.
In addition, we should also be wary of the choice of mabaloxavir** and the purchase channel. When choosing to buy mabaloxavir, it is recommended to choose a reputable and formal channel to buy it, and avoid excessive **.
Finally, we need to keep in mind that anti-influenza drugs are not a substitute for influenza vaccines, and annual influenza vaccination is still the best way to prevent influenza. At the same time, according to the relevant regulations, people who have used mabaloxavir in the 17 days before receiving the live attenuated influenza vaccine are prohibited from vaccination. Therefore, when using drugs, it is necessary to use them rationally under the guidance of physicians and pharmacists, and do not blindly self-medicate.
All in all, mabaloxavir, as a new anti-influenza virus drug, has certain efficacy, but it is limited to patients, and it is necessary to pay attention to drug interactions and dose selection when using it. When buying drugs, you also need to be rational and vigilant, choose the right channel, and avoid ** purchase. Through our joint efforts, we believe that we can effectively deal with the threat of influenza and protect our own health.