Polycystic kidney disease is a genetic disease, manifested by the gradual appearance of multiple cysts of different sizes in the two kidneys from childhood or youth, the cysts grow larger and larger, and normal kidney tissues such as glomeruli are squeezed and atrophied by ischemic atrophy, which is characterized by the formation of multiple cysts in the kidneys, which gradually enlarge and eventually replace the normal kidney tissue.
There are two outcomes:
The first is high blood pressure, after ischemia or damage to normal kidney tissue, it will secrete a substance called renin, which is like a key that activates a "door of terror" (renin-angiotensin-aldosterone system), causing high blood pressure. This kind of blood pressure occurs early, in childhood or young adulthood, and blood pressure remains high, often exceeding 180 110 mmHg, and is difficult to control, and several antihypertensive drugs cannot be lowered to normal.
The second is kidney failure, the cyst grows more and more, grows larger and larger, the glomeruli is compressed and atrophies, the serum creatinine gradually increases, the kidney function gradually declines, and eventually kidney failure and uremia occur. Polycystic kidney disease is one of the common causes of uremia in China.
People with polycystic kidney disease may not have any symptoms in the early stages, but as the disease progresses, the following symptoms may occur:
1.Pain: Pain in the lower back or abdomen, especially on the right side. This pain is usually caused by the cyst enlarged or bleeding.
2.Abdominal mass: People with polycystic kidney disease may have a palpable mass in the abdomen due to the enlargement of the cyst.
3.Renal dysfunction: Patients with polycystic kidney disease may experience renal dysfunction, including uremia, renal failure, etc.
4.Other symptoms: Patients with polycystic kidney disease may also have symptoms such as high blood pressure, anemia, and fever.
Diagnosis of polycystic kidney disease.
The diagnosis of polycystic kidney disease is usually made by imaging tests such as ultrasound, CT, or MRI. These tests can find cysts in the kidneys and assess their size and number. Blood tests can test kidney function and other relevant indicators.
Polycystic kidney disease**.
Methods of polycystic kidney disease include medications, surgery, and dialysis. Medications** are commonly used to relieve symptoms and slow the progression of the condition, including pain relievers, antihypertensive medications, etc. There is no specific drug for polycystic kidney disease, but there are measures to delay the growth of cysts, and the commonly used is tolvaptan, which has been confirmed by a large number of studies, but the application is not popular, and the biggest obstacle is that this drug is more expensive. Controlling blood pressure is the core measure of polycystic kidney disease at present, and the blood pressure can be controlled below 130 80mmHg, and a variety of antihypertensive drugs can be used in combination and increased doses. For larger cysts, symptoms can be reduced by surgery or embolization**. Dialysis is a method of performing in the event of kidney failure, including hemodialysis and peritoneal dialysis.
In conclusion, polycystic kidney disease is a serious chronic kidney disease, and understanding its symptoms, diagnosis, and modalities is essential for a patient's health and quality of life. If you have any concerns or similar symptoms, seek medical attention and receive professional advice**.