Abnormal growth of breast cells caused by various causes can cause breast cancer.
However, the exact cause is still unknown, and some factors that may increase the risk of developing the disease, also known as high-risk factors, have been identified.
Factors such as genetics, endocrine, menstruation, marital and childbearing history are related to the risk of developing the disease, but when it comes to individuals, it does not mean that there are high-risk factors to develop breast cancer.
It's unclear why some individuals with no risk factors develop cancer while others with risk factors don't.
In any case, people at high risk should pay more attention to breast cancer screening.
Genetic factors: It has been suggested that about 5% to 10% of breast cancers are associated with genetic mutations that run in families.
Family history: Sisters and daughters with premenopausal breast cancer in their immediate family are 3 to 8 times more likely to develop breast cancer than those without a family history.
Genetic mutations: If there are mutations in the breast cancer susceptibility genes BRCA-1 and BRCA-2, the probability of developing breast cancer is greatly increased.
Endocrine factors: Estrogen is closely related to the onset of breast cancer, which is one of the reasons why women are more likely to develop breast cancer.
Menstrual marital factors: Young age at menarche, late menopause, and short menstrual cycle are high risk factors for breast cancer.
The incidence is higher in people who are infertile for life, those who have first childbearing older than 30 years, and those who have not breastfed after childbirth.
Diseases of the breast itself: Severe dysplasia of the breast and papillomas are at greater risk of developing breast cancer and are considered precancerous. Large intraductal papillomas have the potential to develop into large intraductal papillomas.
Patients with breast cancer on one side have a 3-4-fold increased risk of developing breast cancer on the opposite side.
Physical factors: Breast tissue is more sensitive to ionizing radiation, and people who are exposed to too much radiation have a greater risk of cancer.
Chest radiation** as a child is associated with an increased risk of breast cancer in adulthood.
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