The relevant effects of commonly used drugs for patients with coronary heart disease Side effects in

Mondo Health Updated on 2024-01-31

Coronary heart disease, a common cardiovascular disease, causes distress in many people's lives. With the advancement of medicine, the best methods of coronary heart disease are also constantly developing and improving. Among them, drugs** are one of the important means of coronary heart disease**. This article will give you a detailed introduction to the types, effects, contraindications and contraindications commonly used in patients with coronary heart disease, to help you have a more comprehensive understanding of the best drugs for coronary heart disease. Let's explore how to bring a better quality of life to patients with coronary heart disease through reasonable drugs**.

1.Antiplatelet aggregation drugs: These drugs are mainly used to inhibit platelet aggregation and prevent thrombosis, thereby reducing the risk of acute myocardial infarction. Common medications include aspirin, clopidogrel, etc.

Aspirin: acts as an antiplatelet aggregation by inhibiting the synthesis of platelet cyclooxygenase and TXA2. It is used to prevent myocardial infarction, stroke and other thrombotic diseases. Long-term use may cause gastrointestinal bleeding or ulcers, and should be used with caution in patients with ulcer disease or bleeding disorders.

Clopidogrel: Selectively inhibits the binding of ADP to platelet receptors, thereby inhibiting platelet aggregation. It is often used in combination with aspirin for secondary prevention in patients with coronary artery disease. It may cause adverse reactions such as bleeding, gastrointestinal reactions, rashes, etc.

Statins: These drugs are mainly used to lower cholesterol and triglycerides in the blood and slow the progression of coronary atherosclerosis. Common medications include rosuvastatin, atorvastatin, etc.

Rosuvastatin: a powerful lipid-lowering drug that can significantly reduce blood LDL-C and total cholesterol levels, stabilize plaques, and reduce the occurrence of acute cardiovascular events. Long-term use may cause adverse reactions such as abnormal liver function and muscle damage. Contraindicated in patients with severe renal insufficiency. Atorvastatin: a commonly used lipid-lowering drug that can significantly reduce blood LDL-C and total cholesterol levels and stabilize plaques. Long-term use may lead to adverse reactions such as abnormal liver function and muscle damage. Do not use in pregnant and lactating women. Receptor blockers: These drugs are mainly used to reduce myocardial oxygen consumption, relieve angina symptoms, and also help reduce the risk of arrhythmias and sudden death. Common medications include metoprolol, bisoprolol, etc.

Metoprolol: a selective 1-receptor blocker that lowers heart rate, lowers blood pressure, and inhibits myocardial contractility, thereby reducing myocardial oxygen consumption and relieving angina symptoms. Long-term use may lead to adverse reactions such as bradycardia, fatigue, and insomnia. Patients with acute heart failure, sick sinus syndrome, and atrioventricular block are contraindicated. Bisoprolol: a selective 1-receptor blocker that lowers heart rate, lowers blood pressure, and inhibits myocardial contractility, thereby reducing myocardial oxygen consumption and relieving angina symptoms. Long-term use may lead to adverse reactions such as bradycardia, fatigue, and insomnia. Patients with acute heart failure, sick sinus syndrome, and atrioventricular block are contraindicated. Nitrates: These drugs are mainly used to dilate the coronary arteries, increase the blood supply to the heart muscle, and relieve angina symptoms. Common drugs include isosorbide dinitrate, isosorbide mononitrate, etc.

Isosorbide dinitrate: Relieves angina pectoris symptoms by dilating coronary arteries and collateral circulation, increasing blood supply to the myocardium. Long-term use may lead to drug resistance and *** such as headache, **flushing, low blood pressure, etc. Contraindicated in patients with glaucoma. Isosorbide mononitrate: a long-acting nitrate drug that dilates coronary arteries, increases blood supply to the myocardium, and relieves angina symptoms. Long-term use may cause adverse reactions such as headache, nausea, vomiting, etc. Contraindicated in patients with glaucoma. ACE inhibitors: These drugs are mainly used to lower blood pressure and improve myocardial remodeling, helping to reduce the burden on the heart and reduce the risk of cardiovascular events. Common drugs include captopril, enalapril, etc.

Captopril: representative of angiotensin-converting enzyme inhibitors, which inhibits ACE activity, thereby lowering blood pressure and improving myocardial remodeling. Long-term use may lead to adverse reactions such as cough, low blood pressure, and kidney damage. Do not use in pregnant and lactating women. Enalapril: an angiotensin-converting enzyme inhibitor that inhibits ACE activity, thereby lowering blood pressure and improving myocardial remodeling. Long-term use may lead to adverse reactions such as cough, low blood pressure, and kidney damage. Do not use in pregnant and lactating women. The above content is for reference only, and the specific medication regimen needs to be determined according to the patient's condition and the doctor's recommendation. Patients should follow the doctor's guidance, take the medicine on time and in the right amount, and pay attention to the body's reaction, and seek medical attention in time if there is any abnormality. At the same time, patients should maintain a healthy lifestyle, reasonable diet, moderate exercise, weight control, etc., in order to comprehensively manage the condition of coronary heart disease.

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